MUC5B

GENE INFORMATION

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Gene name

MUC5B (HGNC Symbol)

Synonyms

MG1, MUC5

Description

Mucin 5B, oligomeric mucus/gel-forming (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

1223066 - 1262172

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000117983 (version 78.38)

Entrez gene

727897

UniProt

Q9HC84 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HC84

Antibodypedia

MUC5B antibodies
 

PROTEIN VIEW

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MUC5B-002
 
MUC5B-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MUC5B-002 ENSP00000436812
ENST00000529681
Q9HC84
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Show » Show » 5762 596.3 Yes 0
MUC5B-005 ENSP00000434539
ENST00000526859
H0YDX8
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Show » Show » 154 16.3 No 0