UBR5

GENE INFORMATION

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Gene name

UBR5 (HGNC Symbol)

Synonyms

DD5, EDD, EDD1, HYD, KIAA0896

Description

Ubiquitin protein ligase E3 component n-recognin 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q22.3

Chromosome location (bp)

102253012 - 102412841

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000104517 (version 78.38)

Entrez gene

51366

UniProt

O95071 (UniProt - Evidence at protein level)

neXtProt

NX_O95071

Antibodypedia

UBR5 antibodies
 

PROTEIN VIEW

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UBR5-001
 
UBR5-002
 
UBR5-003
 
UBR5-004
 
UBR5-008
 
UBR5-009
 
UBR5-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBR5-001 ENSP00000429084
ENST00000520539
O95071
Show all »
Show » Show » 2799 309.4 No 0
UBR5-002 ENSP00000220959
ENST00000220959
O95071
Show all »
Show » Show » 2798 309.2 No 0
UBR5-003 ENSP00000427819
ENST00000521922
E7EMW7
Show all »
Show » Show » 2792 308.6 No 0
UBR5-004 ENSP00000428693
ENST00000518205
E7ET84
Show all »
Show » Show » 527 59.7 No 0
UBR5-008 ENSP00000428138
ENST00000519365
Show » 201 21.6 No 0
UBR5-009 ENSP00000429127
ENST00000520898
Show » 195 20.6 No 0
UBR5-013 ENSP00000428062
ENST00000521566
E5RFK7
Show all »
Show » 166 19.2 No 0