NFAT5

GENE INFORMATION

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Gene name

NFAT5 (HGNC Symbol)

Synonyms

KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP

Description

Nuclear factor of activated T-cells 5, tonicity-responsive (HGNC Symbol)

Entrez gene summary

The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q22.1

Chromosome location (bp)

69565094 - 69704666

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102908 (version 78.38)

Entrez gene

10725

UniProt

O94916 (UniProt - Evidence at protein level)

neXtProt

NX_O94916

Antibodypedia

NFAT5 antibodies
 

PROTEIN VIEW

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NFAT5-001
 
NFAT5-002
 
NFAT5-006
 
NFAT5-007
 
NFAT5-009
 
NFAT5-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NFAT5-001 ENSP00000346420
ENST00000354436
O94916
Show all »
Show » Show » 1531 165.8 No 0
NFAT5-002 ENSP00000377343
ENST00000393742
O94916
Show all »
Show » Show » 1455 158 No 0
NFAT5-006 ENSP00000455628
ENST00000566899
O94916
Show all »
Show » Show » 1455 158 No 0
NFAT5-007 ENSP00000463214
ENST00000565301
J3QKS5
Show all »
Show » Show » 141 14.7 No 0
NFAT5-009 ENSP00000457593
ENST00000567239
O94916
Show all »
Show » Show » 1548 167.7 No 0
NFAT5-201 ENSP00000338806
ENST00000349945
O94916
Show all »
Show » Show » 1455 158 No 0