GNA11

GENE INFORMATION

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Gene name

GNA11 (HGNC Symbol)

Synonyms

FBH, FBH2, FHH2, HHC2

Description

Guanine nucleotide binding protein (G protein), alpha 11 (Gq class) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

3094410 - 3124004

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000088256 (version 78.38)

Entrez gene

2767

UniProt

P29992 (UniProt - Evidence at protein level)

neXtProt

NX_P29992

Antibodypedia

GNA11 antibodies
 

PROTEIN VIEW

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GNA11-001
 
GNA11-003
 
GNA11-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GNA11-001 ENSP00000078429
ENST00000078429
P29992
Show all »
Show » Show » 359 42.1 No 0
GNA11-003 ENSP00000479797
ENST00000588401
Show » Show » 72 8 No 0
GNA11-007 ENSP00000465935
ENST00000587636
Show » Show » 236 27.3 No 0