NDC80

GENE INFORMATION

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Gene name

NDC80 (HGNC Symbol)

Synonyms

HEC, HEC1, hsNDC80, KNTC2, TID3

Description

NDC80 kinetochore complex component (HGNC Symbol)

Entrez gene summary

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]

Chromosome

18

Cytoband

p11.32

Chromosome location (bp)

2571511 - 2616635

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000080986 (version 78.38)

Entrez gene

10403

UniProt

O14777 (UniProt - Evidence at protein level)

neXtProt

NX_O14777

Antibodypedia

NDC80 antibodies
 

PROTEIN VIEW

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NDC80-001
 
NDC80-011
 
NDC80-013
 
NDC80-017
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NDC80-001 ENSP00000261597
ENST00000261597
O14777
Show all »
Show » Show » 642 73.9 No 0
NDC80-011 ENSP00000461227
ENST00000575515
I3L4G3
Show all »
Show » 141 15.4 No 0
NDC80-013 ENSP00000476919
ENST00000576274
V9GYM9
Show all »
Show » 168 18.7 No 0
NDC80-017 ENSP00000458236
ENST00000574096
I3L0P0
Show all »
Show » 32 3.7 No 0