DERL2

GENE INFORMATION

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Gene name

DERL2 (HGNC Symbol)

Synonyms

CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa

Description

Derlin 2 (HGNC Symbol)

Entrez gene summary

Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM, Mar 2008]

Chromosome

17

Cytoband

p13.2

Chromosome location (bp)

5471251 - 5486811

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000072849 (version 78.38)

Entrez gene

51009

UniProt

Q9GZP9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9GZP9

Antibodypedia

DERL2 antibodies
 

PROTEIN VIEW

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DERL2-001
 
DERL2-008
 
DERL2-009
 
DERL2-010
 
DERL2-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DERL2-001 ENSP00000158771
ENST00000158771
Q9GZP9
Show all »
Show » Show » 239 27.6 No 5
DERL2-008 ENSP00000459072
ENST00000570848
I3L1S8
Show all »
Show » 144 17.2 No 4
DERL2-009 ENSP00000458296
ENST00000571971
I3L0R8
Show all »
Show » 200 23.4 No 6
DERL2-010 ENSP00000460671
ENST00000572834
I3L3R8
Show all »
Show » 74 8.8 No 0
DERL2-012 ENSP00000459083
ENST00000575605
I3L1T3
Show all »
Show » 158 18 No 3