Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence summary HPA evidence UniProt evidence MS evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location RNA tissue category RNA TS RNA TS FPKM FPKM max in non-specific ACADS ACAD3, SCAD ENSG00000122971 Acyl-CoA dehydrogenase, C-2 to C-3 short chain 12 120725735-120740008 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004799, CAB019284, HPA022271 Supportive Supportive Nucleus but not nucleoli, Centrosome Expressed in all duodenum: 56.0 ACADSB ACAD7, SBCAD ENSG00000196177 Acyl-CoA dehydrogenase, short/branched chain 10 123008979-123058311 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041458 Uncertain Supportive Mitochondria Expressed in all liver: 122.6 ADI1 APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL ENSG00000182551 Acireductone dioxygenase 1 2 3497361-3519736 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA035403, HPA035404 Uncertain Supportive Nucleus but not nucleoli, Golgi apparatus Expressed in all liver: 172.2 AKR1B1 ALDR1, AR ENSG00000085662 Aldo-keto reductase family 1, member B1 (aldose reductase) 7 134442350-134459284 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB018773, HPA026425, CAB027391, CAB047353, HPA052751 Supportive Supportive Nucleus but not nucleoli, Cytoplasm Tissue enriched 9 adrenal gland: 1545.4 placenta: 174.2 AKR1C2 BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD ENSG00000151632 Aldo-keto reductase family 1, member C2 10 4922564-5135226 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB047304 Uncertain Expressed in all adipose tissue: 203.2 AKR1C3 DDX, HAKRB, HSD17B5, KIAA0119, PGFS ENSG00000196139 Aldo-keto reductase family 1, member C3 10 5035354-5107686 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB010874 Uncertain Expressed in all duodenum: 221.5 AKR7A2 AFAR ENSG00000053371 Aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1 19303965-19312146 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB032587, CAB032841 Supportive Supportive Cytoplasm Expressed in all kidney: 63.6 ALDH1A1 ALDH1, PUMB1, RALDH1 ENSG00000165092 Aldehyde dehydrogenase 1 family, member A1 9 72900662-73080442 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002123, CAB020690 Supportive Expressed in all liver: 481.9 ALDH1A3 ALDH6, RALDH3 ENSG00000184254 Aldehyde dehydrogenase 1 family, member A3 15 100877714-100916626 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA046271, HPA064749 Uncertain Supportive Nucleus, Cytoplasm Tissue enhanced 0 prostate: 119.1 urinary bladder: 49.4 ALDH4A1 ALDH4, P5CDh ENSG00000159423 Aldehyde dehydrogenase 4 family, member A1 1 18871430-18902781 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004645, HPA006401 Supportive Uncertain Cytoplasm Expressed in all kidney: 176.5 ALDH5A1 SSADH, SSDH ENSG00000112294 Aldehyde dehydrogenase 5 family, member A1 6 24494852-24537207 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029715, HPA029716 Supportive Supportive Mitochondria Expressed in all liver: 33.5 ALDH6A1 MMSDH ENSG00000119711 Aldehyde dehydrogenase 6 family, member A1 14 74056850-74084493 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA029072, HPA029073, HPA029074, HPA029075 Supportive Supportive Mitochondria Group enriched 5 kidney: 257.6;liver: 120.0 cerebral cortex: 36.5 ALDH7A1 ATQ1, EPD, PDE ENSG00000164904 Aldehyde dehydrogenase 7 family, member A1 5 126541841-126595418 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023296 Uncertain Supportive Mitochondria, Cytoplasm Mixed kidney: 52.5 ASPH BAH, CASQ2BP1, HAAH, JCTN ENSG00000198363 Aspartate beta-hydroxylase 8 61500556-61714640 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA055161, HPA059303 Uncertain Supportive Endoplasmic reticulum Expressed in all adipose tissue: 266.2 BLVRB FLR, SDR43U1 ENSG00000090013 Biliverdin reductase B (flavin reductase (NADPH)) 19 40447789-40465840 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041698, HPA041937 Supportive Supportive Plasma membrane, Cytoplasm, Nucleus but not nucleoli Expressed in all bone marrow: 295.2 CBR1 CBR, SDR21C1 ENSG00000159228 Carbonyl reductase 1 21 36069941-36073166 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018433 Uncertain Supportive Nucleus, Cytoplasm Expressed in all duodenum: 392.3 CBR3 SDR21C2 ENSG00000159231 Carbonyl reductase 3 21 36134912-36146566 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA018434 Uncertain Supportive Nucleus but not nucleoli, Cytoplasm Mixed esophagus: 12.0 CPOX CPO, CPX, HCP ENSG00000080819 Coproporphyrinogen oxidase 3 98521132-98593723 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA015736, HPA054448 Uncertain Supportive Mitochondria Expressed in all bone marrow: 21.6 CRYZ ENSG00000116791 Crystallin, zeta (quinone reductase) 1 74705482-74733408 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021921, HPA023290 Supportive Supportive Cytoplasm Expressed in all kidney: 189.7 CYB5R1 humb5R2, NQO3A2 ENSG00000159348 Cytochrome b5 reductase 1 1 202961869-202967280 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA010641, HPA014147 Supportive Uncertain Nucleoli, Cytoplasm, Mitochondria Expressed in all skeletal muscle: 144.1 CYB5R3 DIA1 ENSG00000100243 Cytochrome b5 reductase 3 22 42617840-42649568 Cancer-related genes, Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001566 Uncertain Supportive Endoplasmic reticulum Expressed in all adipose tissue: 214.7 DBH DBM ENSG00000123454 Dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9 133636360-133659344 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at transcript level Evidence at protein level Evidence at protein level HPA005960 Uncertain Tissue enriched 15 adrenal gland: 208.3 liver: 14.0 DCXR DCR, KIDCR, SDR20C1 ENSG00000169738 Dicarbonyl/L-xylulose reductase 17 82035136-82037732 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023371, HPA023863 Supportive Uncertain Nucleoli, Cytoskeleton (Microtubules) Expressed in all liver: 500.7 DECR1 DECR, SDR18C1 ENSG00000104325 2,4-dienoyl CoA reductase 1, mitochondrial 8 90001405-90052092 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023160, HPA023162, HPA023238 Supportive Supportive Mitochondria, Cytoplasm Expressed in all liver: 186.0 DHCR24 KIAA0018, seladin-1 ENSG00000116133 24-dehydrocholesterol reductase 1 54849633-54887218 Cytoskeleton related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB037247, HPA063005 Supportive Expressed in all adrenal gland: 721.4 DHTKD1 DKFZP762M115, KIAA1630, MGC3090 ENSG00000181192 Dehydrogenase E1 and transketolase domain containing 1 10 12068972-12123225 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA037949, HPA037950 Uncertain Supportive Mitochondria Expressed in all liver: 46.9 ETHE1 HSCO, YF13H12 ENSG00000105755 Ethylmalonic encephalopathy 1 19 43506719-43527244 Cancer-related genes, Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA028360, HPA029028, HPA029029 Supportive Supportive Mitochondria, Nucleus but not nucleoli Expressed in all rectum: 173.1 FASN FAS, SDR27X1 ENSG00000169710 Fatty acid synthase 17 82078338-82098332 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005192, HPA006461, CAB015417, HPA056108 Supportive Supportive Cytoplasm, Plasma membrane Tissue enriched 5 adipose tissue: 170.3 prostate: 32.1 FDXR ADXR ENSG00000161513 Ferredoxin reductase 17 74862497-74873031 Enzymes, Mitochondrial proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009818, HPA044393, HPA053673 Supportive Tissue enhanced 0 adrenal gland: 126.6 testis: 26.5 G6PD G6PD1 ENSG00000160211 Glucose-6-phosphate dehydrogenase X 154531391-154547572 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000247, HPA000834 Supportive Supportive Cytoplasm, Vesicles, Microtubule organizing center, Centrosome Expressed in all testis: 71.9 GAPDH GAPD ENSG00000111640 Glyceraldehyde-3-phosphate dehydrogenase 12 6533927-6538374 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB005197, CAB016392, HPA040067, HPA061280 Supportive Supportive Plasma membrane, Cytoplasm, Nuclear membrane Expressed in all skeletal muscle: 5958.2 GCDH ACAD5 ENSG00000105607 Glutaryl-CoA dehydrogenase 19 12891026-12914207 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA043252, HPA048492 Supportive Supportive Mitochondria Expressed in all liver: 37.4 GLDC GCSP, NKH ENSG00000178445 Glycine dehydrogenase (decarboxylating) 9 6532464-6645650 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002318, HPA052887 Supportive Supportive Mitochondria, Nucleus Tissue enhanced 0 kidney: 19.2;liver: 11.4;placenta: 12.5 cerebral cortex: 4.5 GPD2 ENSG00000115159 Glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 2 156435290-156613735 Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA008012, HPA045506 Supportive Expressed in all fallopian tube: 21.1 GSR ENSG00000104687 Glutathione reductase 8 30678061-30727926 Cancer-related genes, Enzymes, FDA approved drug targets, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001538, CAB008632 Supportive Supportive Cytoplasm, Plasma membrane Expressed in all rectum: 46.8 H6PD GDH ENSG00000049239 Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1 9234775-9271337 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA004824, HPA005440 Supportive Uncertain Cytoplasm Expressed in all ovary: 30.3 HGD AKU, HGO ENSG00000113924 Homogentisate 1,2-dioxygenase 3 120628173-120682571 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA047374, HPA052359 Supportive Uncertain Nucleus, Nucleoli Tissue enhanced 0 kidney: 79.1;liver: 146.1 gallbladder: 46.3 HSD17B10 17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1 ENSG00000072506 Hydroxysteroid (17-beta) dehydrogenase 10 X 53431258-53434373 Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001432 Uncertain Uncertain Nucleus, Nuclear membrane, Golgi apparatus Expressed in all liver: 95.3 HSD17B11 17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2 ENSG00000198189 Hydroxysteroid (17-beta) dehydrogenase 11 4 87336610-87391386 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021608 Uncertain Supportive Vesicles Expressed in all small intestine: 213.0 HSD17B4 DBP, MFE-2, SDR8C1 ENSG00000133835 Hydroxysteroid (17-beta) dehydrogenase 4 5 119452443-119637199 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA021302, HPA021311, HPA021479 Supportive Supportive Vesicles Expressed in all thyroid gland: 119.8 IDH1 ENSG00000138413 Isocitrate dehydrogenase 1 (NADP+), soluble 2 208236227-208266074 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033218, HPA035248, HPA057936, CAB062556 Supportive Uncertain Nucleus, Cytoplasm Expressed in all adrenal gland: 189.1 IDH3A ENSG00000166411 Isocitrate dehydrogenase 3 (NAD+) alpha 15 78131498-78171949 Citric acid cycle related proteins, Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041465, HPA062971 Supportive Supportive Mitochondria Expressed in all heart muscle: 33.6 IVD ACAD2 ENSG00000128928 Isovaleryl-CoA dehydrogenase 15 40405795-40435947 Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041391, HPA044250 Supportive Supportive Mitochondria, Nucleus but not nucleoli Expressed in all thyroid gland: 90.0 KDSR DHSR, FVT1, SDR35C1 ENSG00000119537 3-ketodihydrosphingosine reductase 18 63327726-63367510 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003673, HPA044884 Uncertain Expressed in all ovary: 30.6 LDHB ENSG00000111716 Lactate dehydrogenase B 12 21635342-21757857 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004641, HPA019007 Supportive Supportive Cytoplasm Expressed in all heart muscle: 1039.2 MAOA ENSG00000189221 Monoamine oxidase A X 43654907-43746824 Disease related genes, Enzymes, FDA approved drug targets, Mitochondrial proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB009437, HPA054807, HPA059299 Supportive Supportive Mitochondria Mixed small intestine: 178.7 MDH2 ENSG00000146701 Malate dehydrogenase 2, NAD (mitochondrial) 7 76048051-76067508 Citric acid cycle related proteins, Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA019714, HPA019716, HPA019848, HPA026720 Supportive Supportive Mitochondria Expressed in all skeletal muscle: 186.7 ME1 ENSG00000065833 Malic enzyme 1, NADP(+)-dependent, cytosolic 6 83210389-83431071 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006493 Uncertain Uncertain Nucleus but not nucleoli, Plasma membrane, Cytoplasm Mixed adrenal gland: 34.7 MPO ENSG00000005381 Myeloperoxidase 17 58269856-58280935 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000059, HPA021147, HPA061464 Supportive Tissue enriched 273 bone marrow: 2067.0 salivary gland: 7.5 MSRA ENSG00000175806 Methionine sulfoxide reductase A 8 10054268-10428891 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023804, HPA053069 Uncertain Supportive Nucleus but not nucleoli, Cytoplasm Expressed in all kidney: 97.9 MTHFD1 MTHFC, MTHFD ENSG00000100714 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 14 64388031-64463457 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000704, HPA001290, HPA015006, HPA050052 Uncertain Expressed in all liver: 131.1 NOS3 ECNOS, eNOS ENSG00000164867 Nitric oxide synthase 3 (endothelial cell) 7 150990995-151014588 Cancer-related genes, Cytoskeleton related proteins, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB002168 Supportive Tissue enriched 8 spleen: 50.1 adipose tissue: 6.0 NQO1 DHQU, DIA4, DTD, NMOR1, QR1 ENSG00000181019 NAD(P)H dehydrogenase, quinone 1 16 69706996-69726951 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA007308, CAB012421 Supportive Supportive Cytoplasm Tissue enhanced 0 stomach: 425.9 gallbladder: 210.9 NSDHL H105e3, SDR31E1, XAP104 ENSG00000147383 NAD(P) dependent steroid dehydrogenase-like X 152830967-152869729 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA000248, HPA000571 Supportive Supportive Endoplasmic reticulum, Vesicles Expressed in all esophagus: 24.2 NXN FLJ12614, NRX ENSG00000167693 Nucleoredoxin 17 799313-979770 Enzymes, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA022850, HPA023566 Supportive Supportive Cytoplasm, Golgi apparatus Mixed endometrium: 26.7 P4HA2 C-P4Halpha(II) ENSG00000072682 Prolyl 4-hydroxylase, alpha polypeptide II 5 132191838-132295315 Enzymes, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA016997, HPA027824, CAB062557 Supportive Supportive Endoplasmic reticulum, Vesicles Expressed in all kidney: 47.3 PDHB ENSG00000168291 Pyruvate dehydrogenase (lipoamide) beta 3 58427630-58433857 Citric acid cycle related proteins, Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB033794, HPA036744, HPA036745 Supportive Supportive Mitochondria, Nucleus but not nucleoli Expressed in all heart muscle: 93.5 PGD ENSG00000142657 Phosphogluconate dehydrogenase 1 10398592-10420144 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA031314, HPA031315 Uncertain Uncertain Cytoplasm, Cytoskeleton (Intermediate filaments) Expressed in all esophagus: 321.8 PHGDH PDG, PGDH, SERA ENSG00000092621 Phosphoglycerate dehydrogenase 1 119659798-119744215 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB003681, HPA021241, HPA024031, CAB068216 Supportive Supportive Nucleus but not nucleoli, Plasma membrane, Cytoplasm Mixed salivary gland: 76.5 PLOD1 LH1, LLH, PLOD ENSG00000083444 Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1 11934205-11975538 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA049137, HPA055799 Uncertain Uncertain Vesicles, Nucleus but not nucleoli Expressed in all placenta: 73.7 PLOD3 LH3 ENSG00000106397 Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 7 101205977-101218420 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001236 Uncertain Expressed in all placenta: 31.3 PNPO PDXPO ENSG00000108439 Pyridoxamine 5'-phosphate oxidase 17 47941506-47948288 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA023204, HPA027776 Supportive Supportive Nucleus but not nucleoli, Cytoplasm Expressed in all liver: 36.5 POR CYPOR, FLJ26468 ENSG00000127948 P450 (cytochrome) oxidoreductase 7 75899200-75986855 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004372, HPA010136 Supportive Uncertain Nucleus but not nucleoli, Vesicles Expressed in all liver: 154.3 PRDX1 NKEFA, PAGA ENSG00000117450 Peroxiredoxin 1 1 45511036-45523047 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB004682, HPA007730 Supportive Supportive Mitochondria Expressed in all thyroid gland: 611.9 PRDX2 MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA ENSG00000167815 Peroxiredoxin 2 19 12796820-12801859 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008713 Uncertain Expressed in all heart muscle: 347.2 PRDX3 AOP-1, AOP1, MER5, SP-22 ENSG00000165672 Peroxiredoxin 3 10 119167703-119178833 Enzymes, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008656, HPA041488 Supportive Expressed in all adrenal gland: 295.5 PRDX4 AOE37-2 ENSG00000123131 Peroxiredoxin 4 X 23664262-23686399 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008659, CAB027389 Supportive Expressed in all pancreas: 251.9 PRDX5 ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10 ENSG00000126432 Peroxiredoxin 5 11 64318088-64321811 Enzymes, FDA approved drug targets, Mitochondrial proteins, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB008661, HPA037915, HPA037916 Supportive Supportive Cytoplasm, Mitochondria Expressed in all fallopian tube: 377.8 PRDX6 1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX ENSG00000117592 Peroxiredoxin 6 1 173477266-173488807 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA006983, CAB008663 Supportive Supportive Plasma membrane, Cytoplasm, Nucleus but not nucleoli Expressed in all adipose tissue: 240.0 PTGS1 COX1, PGHS-1, PTGHS ENSG00000095303 Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 9 122370530-122395703 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA002834, CAB020315 Supportive Supportive Golgi apparatus, Vesicles Tissue enhanced 0 skin: 90.8 esophagus: 63.8 RRM2B p53R2 ENSG00000048392 Ribonucleotide reductase M2 B (TP53 inducible) 8 102204502-102239118 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB006854, HPA028812 Uncertain Supportive Nucleus but not nucleoli, Cytoplasm Expressed in all thyroid gland: 36.3 SOD1 ALS, ALS1, IPOA ENSG00000142168 Superoxide dismutase 1, soluble 21 31659622-31668931 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001401, CAB008670 Supportive Supportive Nucleus, Cytoplasm, Plasma membrane Expressed in all liver: 629.6 SOD2 ENSG00000112096 Superoxide dismutase 2, mitochondrial 6 159669057-159762529 Cancer-related genes, Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA001814, CAB002013 Supportive Expressed in all bone marrow: 567.3 SPR SDR38C1 ENSG00000116096 Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 2 72887360-72892158 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA039505 Uncertain Supportive Nucleus but not nucleoli, Cytoplasm Mixed colon: 29.3 TYR OCA1, OCA1A, OCAIA ENSG00000077498 Tyrosinase 11 89177452-89295759 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB000079 Supportive Tissue enriched 186 skin: 18.5 adipose tissue: 0.0 UGDH ENSG00000109814 UDP-glucose 6-dehydrogenase 4 39498755-39528311 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level CAB034444, HPA036656, HPA036657 Supportive Supportive Nucleus Expressed in all colon: 80.3 UQCRFS1 RIP1, RIS1, RISP, UQCR5 ENSG00000169021 Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 19 29205321-29213541 Enzymes, Mitochondrial proteins, Predicted intracellular proteins Evidence at protein level Evidence at protein level Evidence at protein level Evidence at protein level HPA041863, HPA050339 Supportive Supportive Mitochondria Expressed in all skeletal muscle: 47.0