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Citing the Human Protein Atlas
To cite us, please use:
The Human Protein Atlas
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Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson Å, Kampf C, Sjöstedt E, Asplund A, Olsson I, Edlund K, Lundberg E, Navani S, Szigyarto CA, Odeberg J, Djureinovic D, Takanen JO, Hober S, Alm T, Edqvist PH, Berling H, Tegel H, Mulder J, Rockberg J, Nilsson P, Schwenk JM, Hamsten M, von Feilitzen K, Forsberg M, Persson L, Johansson F, Zwahlen M, von Heijne G, Nielsen J, Pontén F.
Tissue-based map of the human proteome.
Science 2015 347(6220):1260419.
PubMed: 25613900 DOI: 10.1126/science.1260419
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Uhlen M, Oksvold P, Fagerberg L, Lundberg E, Jonasson K, Forsberg M, Zwahlen M, Kampf C, Wester K, Hober S, Wernerus H, Björling L, Ponten F.
Towards a knowledge-based Human Protein Atlas.
Nat Biotechnol. 2010 28(12):1248-50.
PubMed: 21139605 DOI: 10.1038/nbt1210-1248
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The original Human Protein Atlas publication
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Uhlén M, Björling E, Agaton C, Szigyarto CA, Amini B, Andersen E, Andersson AC, Angelidou P, Asplund A, Asplund C, Berglund L, Bergström K, Brumer H, Cerjan D, Ekström M, Elobeid A, Eriksson C, Fagerberg L, Falk R, Fall J, Forsberg M, Björklund MG, Gumbel K, Halimi A, Hallin I, Hamsten C, Hansson M, Hedhammar M, Hercules G, Kampf C, Larsson K, Lindskog M, Lodewyckx W, Lund J, Lundeberg J, Magnusson K, Malm E, Nilsson P, Odling J, Oksvold P, Olsson I, Oster E, Ottosson J, Paavilainen L, Persson A, Rimini R, Rockberg J, Runeson M, Sivertsson A, Sköllermo A, Steen J, Stenvall M, Sterky F, Strömberg S, Sundberg M, Tegel H, Tourle S, Wahlund E, Waldén A, Wan J, Wernérus H, Westberg J, Wester K, Wrethagen U, Xu LL, Hober S, Pontén F.
A human protein atlas for normal and cancer tissues based on antibody proteomics.
Mol Cell Proteomics. 2005 4(12):1920-32.
PubMed: 16127175 DOI: 10.1074/mcp.M500279-MCP200
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Pathology
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Pontén F, Jirström K, Uhlen M.
The Human Protein Atlas - a tool for pathology.
J Pathol. 2008 216(4):387-93.
PubMed: 18853439 DOI: 10.1002/path.2440
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Publications
| 355 |
Ayoglu B, Birgersson E, Mezger A, Nilsson M, Uhlén M, Nilsson P, Schwenk JM.
Multiplexed protein profiling by sequential affinity capture.
Proteomics. 2016 Epub ahead of print
PubMed: 26935855 DOI: 10.1002/pmic.201500398
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| 354 |
Ayoglu B, Mitsios N, Kockum I, Khademi M, Zandian A, Sjöberg R, Forsström B, Bredenberg J, Lima Bomfim I, Holmgren E, Grönlund H, Guerreiro-Cacais AO, Abdelmagid N, Uhlén M, Waterboer T, Alfredsson L, Mulder J, Schwenk JM, Olsson T, Nilsson P.
Anoctamin 2 identified as an autoimmune target in multiple sclerosis.
Proc Natl Acad Sci U S A. 2016 113(8):2188-93.
PubMed: 26862169 DOI: 10.1073/pnas.1518553113
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| 353 |
Fredolini C, Byström S, Pin E, Edfors F, Tamburro D, Iglesias MJ, Häggmark A, Hong MG, Uhlen M, Nilsson P, Schwenk JM.
Immunocapture strategies in translational proteomics.
Expert Rev Proteomics. 2016 13(1):83-98.
PubMed: 26558424 DOI: 10.1586/14789450.2016.1111141
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| 352 |
Zhang MD, Barde S, Szodorai E, Josephson A, Mitsios N, Watanabe M, Attems J, Lubec G, Kovács GM, Uhlén M, Mulder J, Harkany T, Hökfelt T.
Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord.
Brain Struct Funct. 2016 Epub ahead of print
PubMed: 26843217 DOI: 10.1007/s00429-016-1191-3
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| 351 |
Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS.
Systems Proteomics View of the Endogenous Human Claudin Protein Family.
J Proteome Res. 2016 15(2):339-59.
PubMed: 26680015 DOI: 10.1021/acs.jproteome.5b00769
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| 350 |
Sjöberg R, Mattsson C, Andersson E, Hellström C, Uhlen M, Schwenk JM, Ayoglu B, Nilsson P.
Exploration of high-density protein microarrays for antibody validation and autoimmunity profiling.
N Biotechnol. 2015 Epub ahead of print
PubMed: 26417875 DOI: 10.1016/j.nbt.2015.09.002
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| 349 |
Kanatani S, Honda T, Aramaki M, Hayashi K, Kubo K, Ishida M, Tanaka DH, Kawauchi T, Sekine K, Kusuzawa S, Kawasaki T, Hirata T, Tabata H, Uhlén P, Nakajima K.
The COUP-TFII/Neuropilin-2 is a molecular switch steering diencephalon-derived GABAergic neurons in the developing mouse brain.
Proc Natl Acad Sci U S A. 2015 112(36):E4985-94.
PubMed: 26305926 DOI: 10.1073/pnas.1420701112
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| 348 |
Adori C, Barde S, Vas S, Ebner K, Su J, Svensson C, Mathé AA, Singewald N, Reinscheid RR, Uhlén M, Kultima K, Bagdy G, Hökfelt T.
Exploring the role of neuropeptide S in the regulation of arousal: a functional anatomical study.
Brain Struct Funct. 2015 Epub ahead of print
PubMed: 26462664 DOI: 10.1007/s00429-015-1117-5
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| 347 |
Zieba A, Sjöstedt E, Olovsson M, Fagerberg L, Hallström BM, Oskarsson L, Edlund K, Tolf A, Uhlen M, Ponten F.
The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling.
OMICS. 2015 19(11):659-68.
PubMed: 26488136 DOI: 10.1089/omi.2015.0115
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| 346 |
Dijksterhuis JP, Arthofer E, Marinescu VD, Nelander S, Uhlén M, Pontén F, Mulder J, Schulte G.
High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes.
Exp Cell Res. 2015 339(2):280-8.
PubMed: 26511503 DOI: 10.1016/j.yexcr.2015.10.022
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| 345 |
Björnson E, Mukhopadhyay B, Asplund A, Pristovsek N, Cinar R, Romeo S, Uhlen M, Kunos G, Nielsen J, Mardinoglu A.
Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization.
Cell Rep. 2015 13(9):2014-26.
PubMed: 26655911 DOI: 10.1016/j.celrep.2015.10.045
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| 344 |
Habuka M, Fagerberg L, Hallström BM, Pontén F, Yamamoto T, Uhlen M.
The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling.
PLoS One. 2015 10(12):e0145301.
PubMed: 26694548 DOI: 10.1371/journal.pone.0145301
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| 343 |
Ko BK, Lee SY, Lee YH, Hwang IS, Persson H, Rockberg J, Borrebaeck C, Park D, Kim KT, Uhlen M, Lee JS.
Combination of novel HER2-targeting antibody 1E11 with trastuzumab shows synergistic antitumor activity in HER2-positive gastric cancer.
Mol Oncol. 2015 9(2):398-408.
PubMed: 25306393 DOI: 10.1016/j.molonc.2014.09.007
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| 342 |
Pronk JT, Lee SY, Lievense J, Pierce J, Palsson B, Uhlen M, Nielsen J.
How to set up collaborations between academia and industrial biotech companies.
Nat Biotechnol. 2015 33(3):237-40.
PubMed: 25748909 DOI: 10.1038/nbt.3171
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| 341 |
Perisic L, Rodriguez PQ, Hultenby K, Sun Y, Lal M, Betsholtz C, Uhlén M, Wernerson A, Hedin U, Pikkarainen T, Tryggvason K, Patrakka J.
Schip1 is a novel podocyte foot process protein that mediates actin cytoskeleton rearrangements and forms a complex with Nherf2 and ezrin.
PLoS One. 2015 10(3):e0122067.
PubMed: 25807495 DOI: 10.1371/journal.pone.0122067
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| 340 |
Lundqvist M, Edfors F, Sivertsson Å, Hallström BM, Hudson EP, Tegel H, Holmberg A, Uhlén M, Rockberg J.
Solid-phase cloning for high-throughput assembly of single and multiple DNA parts.
Nucleic Acids Res. 2015 43(7):e49.
PubMed: 25618848 DOI: 10.1093/nar/gkv036
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| 339 |
Forsström B, Axnäs BB, Rockberg J, Danielsson H, Bohlin A, Uhlen M.
Dissecting antibodies with regards to linear and conformational epitopes.
PLoS One. 2015 10(3):e0121673.
PubMed: 25816293 DOI: 10.1371/journal.pone.0121673
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| 338 |
Väremo L, Scheele C, Broholm C, Mardinoglu A, Kampf C, Asplund A, Nookaew I, Uhlén M, Pedersen BK, Nielsen J.
Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes.
Cell Rep. 2015 11(6):921-33.
PubMed: 25937284 DOI: 10.1016/j.celrep.2015.04.010
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| 337 |
Kürten C, Uhlén M, Syrén PO.
Overexpression of functional human oxidosqualene cyclase in Escherichia coli.
Protein Expr Purif. 2015 115():46-53.
PubMed: 25962741 DOI: 10.1016/j.pep.2015.04.015
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| 336 |
Huang M, Bai Y, Sjostrom SL, Hallström BM, Liu Z, Petranovic D, Uhlén M, Joensson HN, Andersson-Svahn H, Nielsen J.
Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast.
Proc Natl Acad Sci U S A. 2015 112(34):E4689-96.
PubMed: 26261321 DOI: 10.1073/pnas.1506460112
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| 335 |
Adori C, Barde S, Bogdanovic N, Uhlén M, Reinscheid RR, Kovacs GG, Hökfelt T.
Neuropeptide S- and Neuropeptide S receptor-expressing neuron populations in the human pons.
Front Neuroanat. 2015 9():126.
PubMed: 26441556 DOI: 10.3389/fnana.2015.00126
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| 334 |
Romanov RA, Alpár A, Zhang MD, Zeisel A, Calas A, Landry M, Fuszard M, Shirran SL, Schnell R, Dobolyi Á, Oláh M, Spence L, Mulder J, Martens H, Palkovits M, Uhlen M, Sitte HH, Botting CH, Wagner L, Linnarsson S, Hökfelt T, Harkany T.
A secretagogin locus of the mammalian hypothalamus controls stress hormone release.
EMBO J. 2015 34(1):36-54.
PubMed: 25430741 DOI: 10.15252/embj.201488977
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| 333 |
Ádori C, Glück L, Barde S, Yoshitake T, Kovacs GG, Mulder J, Maglóczky Z, Havas L, Bölcskei K, Mitsios N, Uhlén M, Szolcsányi J, Kehr J, Rönnbäck A, Schwartz T, Rehfeld JF, Harkany T, Palkovits M, Schulz S, Hökfelt T.
Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease.
Acta Neuropathol. 2015 129(4):541-63.
PubMed: 25676386 DOI: 10.1007/s00401-015-1394-3
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| 332 |
Qundos U, Drobin K, Mattsson C, Hong MG, Sjöberg R, Forsström B, Solomon D, Uhlén M, Nilsson P, Michaëlsson K, Schwenk JM.
Affinity proteomics discovers decreased levels of AMFR in plasma from Osteoporosis patients.
Proteomics Clin Appl. 2015 Epub ahead of print
PubMed: 25689831 DOI: 10.1002/prca.201400167
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| 331 |
Arner P, Henjes F, Schwenk JM, Darmanis S, Dahlman I, Iresjö BM, Naredi P, Agustsson T, Lundholm K, Nilsson P, Rydén M.
Circulating carnosine dipeptidase 1 associates with weight loss and poor prognosis in gastrointestinal cancer.
PLoS One. 2015 10(4):e0123566.
PubMed: 25898255 DOI: 10.1371/journal.pone.0123566
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| 330 |
Hamsten C, Skattum L, Truedsson L, von Döbeln U, Uhlén M, Schwenk JM, Hammarström L, Nilsson P, Neiman M.
Heat differentiated complement factor profiling.
J Proteomics. 2015 126():155-62.
PubMed: 26047714 DOI: 10.1016/j.jprot.2015.05.027
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| 329 |
Häggmark A, Schwenk JM, Nilsson P.
Neuroproteomic profiling of human body fluids.
Proteomics Clin Appl. 2015 Epub ahead of print
PubMed: 26286680 DOI: 10.1002/prca.201500065
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| 328 |
O'Hurley G, Busch C, Fagerberg L, Hallström BM, Stadler C, Tolf A, Lundberg E, Schwenk JM, Jirström K, Bjartell A, Gallagher WM, Uhlén M, Pontén F.
Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer.
PLoS One. 2015 10(8):e0133449.
PubMed: 26237329 DOI: 10.1371/journal.pone.0133449
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| 327 |
Horvatovich P, Lundberg EK, Chen YJ, Sung TY, He F, Nice EC, Goode RJ, Yu S, Ranganathan S, Baker MS, Domont GB, Velasquez E, Li D, Liu S, Wang Q, He QY, Menon R, Guan Y, Corrales FJ, Segura V, Casal JI, Pascual-Montano A, Albar JP, Fuentes M, Gonzalez-Gonzalez M, Diez P, Ibarrola N, Degano RM, Mohammed Y, Borchers CH, Urbani A, Soggiu A, Yamamoto T, Salekdeh GH, Archakov A, Ponomarenko E, Lisitsa A, Lichti CF, Mostovenko E, Kroes RA, Rezeli M, Végvári Á, Fehniger TE, Bischoff R, Vizcaíno JA, Deutsch EW, Lane L, Nilsson CL, Marko-Varga G, Omenn GS, Jeong SK, Lim JS, Paik YK, Hancock WS.
Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project.
J Proteome Res. 2015 Epub ahead of print
PubMed: 26076068 DOI: 10.1021/pr5013009
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| 326 |
Omenn GS, Lane L, Lundberg EK, Beavis RC, Nesvizhskii AI, Deutsch EW.
Metrics for the Human Proteome Project 2015: Progress on the Human Proteome and Guidelines for High-Confidence Protein Identification.
J Proteome Res. 2015 Epub ahead of print
PubMed: 26155816 DOI: 10.1021/acs.jproteome.5b00499
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| 325 |
Roy A, Coum A, Marinescu VD, Põlajeva J, Smits A, Nelander S, Uhrbom L, Westermark B, Forsberg-Nilsson K, Pontén F, Tchougounova E.
Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells.
Oncotarget. 2015 Epub ahead of print
PubMed: 26164207
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| 324 |
Lindskog C, Linné J, Fagerberg L, Hallström BM, Sundberg CJ, Lindholm M, Huss M, Kampf C, Choi H, Liem DA, Ping P, Väremo L, Mardinoglu A, Nielsen J, Larsson E, Pontén F, Uhlén M.
The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling.
BMC Genomics. 2015 16():475.
PubMed: 26109061 DOI: 10.1186/s12864-015-1686-y
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| 323 |
Yu NY, Hallström BM, Fagerberg L, Ponten F, Kawaji H, Carninci P, Forrest AR, Fantom Consortium T, Hayashizaki Y, Uhlén M, Daub CO.
Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium.
Nucleic Acids Res. 2015 43(14):6787-98.
PubMed: 26117540 DOI: 10.1093/nar/gkv608
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| 322 |
Reyahi A, Nik AM, Ghiami M, Gritli-Linde A, Pontén F, Johansson BR, Carlsson P.
Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier.
Dev Cell. 2015 34(1):19-32.
PubMed: 26120030 DOI: 10.1016/j.devcel.2015.05.008
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| 321 |
Sorbye H, Dragomir A, Sundström M, Pfeiffer P, Thunberg U, Bergfors M, Aasebø K, Eide GE, Ponten F, Qvortrup C, Glimelius B.
High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort.
PLoS One. 2015 10(6):e0131046.
PubMed: 26121270 DOI: 10.1371/journal.pone.0131046
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| 320 |
Sjöstedt E, Fagerberg L, Hallström BM, Häggmark A, Mitsios N, Nilsson P, Pontén F, Hökfelt T, Uhlén M, Mulder J.
Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex.
PLoS One. 2015 10(6):e0130028.
PubMed: 26076492 DOI: 10.1371/journal.pone.0130028
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Vizoso M, Ferreira HJ, Lopez-Serra P, Carmona FJ, Martínez-Cardús A, Girotti MR, Villanueva A, Guil S, Moutinho C, Liz J, Portela A, Heyn H, Moran S, Vidal A, Martinez-Iniesta M, Manzano JL, Fernandez-Figueras MT, Elez E, Muñoz-Couselo E, Botella-Estrada R, Berrocal A, Pontén F, Oord Jv, Gallagher WM, Frederick DT, Flaherty KT, McDermott U, Lorigan P, Marais R, Esteller M.
Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR.
Nat Med. 2015 21(7):741-50.
PubMed: 26030178 DOI: 10.1038/nm.3863
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Kiflemariam S, Ljungström V, Pontén F, Sjöblom T.
Tumor vessel up-regulation of INSR revealed by single-cell expression analysis of the tyrosine kinome and phosphatome in human cancers.
Am J Pathol. 2015 185(6):1600-9.
PubMed: 25864925 DOI: 10.1016/j.ajpath.2015.02.019
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Ghaffari P, Mardinoglu A, Asplund A, Shoaie S, Kampf C, Uhlen M, Nielsen J.
Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling.
Sci Rep. 2015 5():8183.
PubMed: 25640694 DOI: 10.1038/srep08183
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Lindskog C.
The potential clinical impact of the tissue-based map of the human proteome.
Expert Rev Proteomics. 2015 12(3):213-5.
PubMed: 25925092 DOI: 10.1586/14789450.2015.1040771
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Mattsson JS, Bergman B, Grinberg M, Edlund K, Marincevic M, Jirström K, Pontén F, Hengstler JG, Rahnenführer J, Karlsson MG, Karlsson C, Helenius G, Botling J, Micke P, Gulyas M.
Prognostic impact of COX-2 in non-small cell lung cancer: a comprehensive compartment-specific evaluation of tumor and stromal cell expression.
Cancer Lett. 2015 356(2 Pt B):837-45.
PubMed: 25449785 DOI: 10.1016/j.canlet.2014.10.032
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Edqvist PH, Fagerberg L, Hallström BM, Danielsson A, Edlund K, Uhlén M, Pontén F.
Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling.
J Histochem Cytochem. 2015 63(2):129-41.
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Lindskog C, Edlund K, Mattsson JS, Micke P.
Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?
Expert Rev Mol Diagn. 2015 15(4):471-90.
PubMed: 25599124 DOI: 10.1586/14737159.2015.1002772
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Häggmark A, Hamsten C, Wiklundh E, Lindskog C, Mattsson C, Andersson E, Lundberg IE, Grönlund H, Schwenk JM, Eklund A, Grunewald J, Nilsson P.
Proteomic profiling reveals autoimmune targets in sarcoidosis.
Am J Respir Crit Care Med. 2015 191(5):574-83.
PubMed: 25608002 DOI: 10.1164/rccm.201407-1341OC
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Edqvist PH, Huvila J, Forsström B, Talve L, Carpén O, Salvesen HB, Krakstad C, Grénman S, Johannesson H, Ljungqvist O, Uhlén M, Pontén F, Auranen A.
Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma.
Gynecol Oncol. 2015 Epub ahead of print
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Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson Å, Kampf C, Sjöstedt E, Asplund A, Olsson I, Edlund K, Lundberg E, Navani S, Szigyarto CA, Odeberg J, Djureinovic D, Takanen JO, Hober S, Alm T, Edqvist PH, Berling H, Tegel H, Mulder J, Rockberg J, Nilsson P, Schwenk JM, Hamsten M, von Feilitzen K, Forsberg M, Persson L, Johansson F, Zwahlen M, von Heijne G, Nielsen J, Pontén F.
Tissue-based map of the human proteome.
Science 2015 347(6220):1260419.
PubMed: 25613900 DOI: 10.1126/science.1260419
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Andersson S, Nilsson K, Fagerberg L, Hallström BM, Sundström C, Danielsson A, Edlund K, Uhlen M, Asplund A.
The transcriptomic and proteomic landscapes of bone marrow and secondary lymphoid tissues.
PLoS One. 2014 9(12):e115911.
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Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications.
Diabetes. 2014 63(11):3785-97.
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Habuka M, Fagerberg L, Hallström BM, Kampf C, Edlund K, Sivertsson Å, Yamamoto T, Pontén F, Uhlén M, Odeberg J.
The kidney transcriptome and proteome defined by transcriptomics and antibody-based profiling.
PLoS One. 2014 9(12):e116125.
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Danielsson A, Pontén F, Fagerberg L, Hallström BM, Schwenk JM, Uhlén M, Korsgren O, Lindskog C.
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One. 2014 9(12):e115421.
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Tyrosine phosphorylation profiling via in situ proximity ligation assay.
BMC Cancer. 2014 14():435.
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Generation of HER2 monoclonal antibodies using epitopes of a rabbit polyclonal antibody.
N Biotechnol. 2014 31(1):35-43.
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Expression and prognostic significance of the polymeric immunoglobulin receptor in epithelial ovarian cancer.
J Ovarian Res. 2014 7(1):26.
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A chromosome-centric analysis of antibodies directed toward the human proteome using Antibodypedia.
J Proteome Res. 2014 13(3):1669-76.
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Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury.
Proc Natl Acad Sci U S A. 2014 111(12):E1149-58.
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Stadler C, Fagerberg L, Sivertsson Å, Oksvold P, Zwahlen M, Hallström BM, Lundberg E, Uhlén M.
RNA- and antibody-based profiling of the human proteome with focus on chromosome 19.
J Proteome Res. 2014 13(4):2019-27.
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HMG-CoA reductase expression in primary colorectal cancer correlates with favourable clinicopathological characteristics and an improved clinical outcome.
Diagn Pathol. 2014 9():78.
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Expression and prognostic significance of the polymeric immunoglobulin receptor in esophageal and gastric adenocarcinoma.
J Transl Med. 2014 12():83.
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Reduced expression of ezrin in urothelial bladder cancer signifies more advanced tumours and an impaired survival: validatory study of two independent patient cohorts.
BMC Urol. 2014 14():36.
PubMed: 24885195 DOI: 10.1186/1471-2490-14-36
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Improved production of a heterologous amylase in Saccharomyces cerevisiae by inverse metabolic engineering.
Appl Environ Microbiol. 2014 80(17):5542-50.
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Defining the Human Adipose Tissue Proteome To Reveal Metabolic Alterations in Obesity.
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Human Cytomegalovirus Tegument Protein pp65 Is Detected in All Intra- and Extra-Axial Brain Tumours Independent of the Tumour Type or Grade.
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The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling.
FASEB J. 2014 Epub ahead of print
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A prognosis based classification of undifferentiated uterine sarcomas: Identification of mitotic index, hormone receptors and YWHAE-FAM22 translocation status as predictors of survival.
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Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer.
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Am J Clin Pathol. 2014 141(5):630-8.
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Molecular- and organelle-based predictive paradigm underlying recovery by left ventricular assist device support.
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Mol Hum Reprod. 2014 20(6):476-88.
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Methods. 2014 Epub ahead of print
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PTPN6 expression is epigenetically regulated and influences survival and response to chemotherapy in high-grade gliomas.
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Diabetologia. 2014 57(3):645-6.
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A systematic analysis of commonly used antibodies in cancer diagnostics.
Histopathology. 2014 64(2):293-305.
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Mol Cell Proteomics. 2014 13(2):397-406.
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J R Soc Med. 2014 107(1):22-9.
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Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria.
PLoS Pathog. 2014 10(4):e1004038.
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Integration of cardiac proteome biology and medicine by a specialized knowledgebase.
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Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium.
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Developments in biobanking workflow standardization providing sample integrity and stability.
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A texture based pattern recognition approach to distinguish melanoma from non-melanoma cells in histopathological tissue microarray sections.
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Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner.
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Investigation of Molecular Alterations of AKT-3 in Triple Negative Breast Cancer.
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Improving the diagnosis and management of neuroendocrine tumors: utilizing new advances in biomarker and molecular imaging science.
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PubMed: 17072308 DOI: 10.1038/nmeth947
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| 20 |
Steen J, Uhlén M, Hober S, Ottosson J.
High-throughput protein purification using an automated set-up for high-yield affinity chromatography.
Protein Expr Purif. 2006 46(2):173-8.
PubMed: 16483795 DOI: 10.1016/j.pep.2005.12.010
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| 19 |
Andrade J, Berglund L, Uhlén M, Odeberg J.
Using Grid technology for computationally intensive applied bioinformatics analyses.
In Silico Biol. 2006 6(6):495-504.
PubMed: 17518760
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| 18 |
Persson A, Hober S, Uhlén M.
A human protein atlas based on antibody proteomics.
Curr Opin Mol Ther. 2006 8(3):185-90.
PubMed: 16774037
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| 17 |
Ek S, Andréasson U, Hober S, Kampf C, Pontén F, Uhlén M, Merz H, Borrebaeck CA.
From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies.
Mol Cell Proteomics. 2006 5(6):1072-81.
PubMed: 16524965 DOI: 10.1074/mcp.M600077-MCP200
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| 16 |
Eriksson C, Agaton C, Kånge R, Sundberg M, Nilsson P, Ek B, Uhlén M, Gustafsson M, Hober S.
Microfluidic analysis of antibody specificity in a compact disk format.
J Proteome Res. 2006 5(7):1568-74.
PubMed: 16823963 DOI: 10.1021/pr050447c
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| 15 |
Haab BB, Paulovich AG, Anderson NL, Clark AM, Downing GJ, Hermjakob H, Labaer J, Uhlen M.
A reagent resource to identify proteins and peptides of interest for the cancer community: a workshop report.
Mol Cell Proteomics. 2006 5(10):1996-2007.
PubMed: 16867976 DOI: 10.1074/mcp.T600020-MCP200
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| 14 |
Larsson K, Wester K, Nilsson P, Uhlén M, Hober S, Wernérus H.
Multiplexed PrEST immunization for high-throughput affinity proteomics.
J Immunol Methods. 2006 315(1-2):110-20.
PubMed: 16949094 DOI: 10.1016/j.jim.2006.07.014
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| 13 |
Andersson AC, Strömberg S, Bäckvall H, Kampf C, Uhlen M, Wester K, Pontén F.
Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics.
J Histochem Cytochem. 2006 54(12):1413-23.
PubMed: 16957166 DOI: 10.1369/jhc.6A7001.2006
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| 12 |
Rada-Iglesias A, Wallerman O, Koch C, Ameur A, Enroth S, Clelland G, Wester K, Wilcox S, Dovey OM, Ellis PD, Wraight VL, James K, Andrews R, Langford C, Dhami P, Carter N, Vetrie D, Pontén F, Komorowski J, Dunham I, Wadelius C.
Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays.
Hum Mol Genet. 2005 14(22):3435-47.
PubMed: 16221759 DOI: 10.1093/hmg/ddi378
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| 11 |
Janzi M, Odling J, Pan-Hammarström Q, Sundberg M, Lundeberg J, Uhlén M, Hammarström L, Nilsson P.
Serum microarrays for large scale screening of protein levels.
Mol Cell Proteomics. 2005 4(12):1942-7.
PubMed: 16131484 DOI: 10.1074/mcp.M500213-MCP200
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| 10 |
Nilsson P, Paavilainen L, Larsson K, Odling J, Sundberg M, Andersson AC, Kampf C, Persson A, Al-Khalili Szigyarto C, Ottosson J, Björling E, Hober S, Wernérus H, Wester K, Pontén F, Uhlen M.
Towards a human proteome atlas: high-throughput generation of mono-specific antibodies for tissue profiling.
Proteomics. 2005 5(17):4327-37.
PubMed: 16237735 DOI: 10.1002/pmic.200500072
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| 9 |
Hedhammar M, Stenvall M, Lönneborg R, Nord O, Sjölin O, Brismar H, Uhlén M, Ottosson J, Hober S.
A novel flow cytometry-based method for analysis of expression levels in Escherichia coli, giving information about precipitated and soluble protein.
J Biotechnol. 2005 119(2):133-46.
PubMed: 15996784 DOI: 10.1016/j.jbiotec.2005.03.024
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| 8 |
Stenvall M, Steen J, Uhlén M, Hober S, Ottosson J.
High-throughput solubility assay for purified recombinant protein immunogens.
Biochim Biophys Acta. 2005 1752(1):6-10.
PubMed: 16084133 DOI: 10.1016/j.bbapap.2005.07.002
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| 7 |
Uhlén M, Björling E, Agaton C, Szigyarto CA, Amini B, Andersen E, Andersson AC, Angelidou P, Asplund A, Asplund C, Berglund L, Bergström K, Brumer H, Cerjan D, Ekström M, Elobeid A, Eriksson C, Fagerberg L, Falk R, Fall J, Forsberg M, Björklund MG, Gumbel K, Halimi A, Hallin I, Hamsten C, Hansson M, Hedhammar M, Hercules G, Kampf C, Larsson K, Lindskog M, Lodewyckx W, Lund J, Lundeberg J, Magnusson K, Malm E, Nilsson P, Odling J, Oksvold P, Olsson I, Oster E, Ottosson J, Paavilainen L, Persson A, Rimini R, Rockberg J, Runeson M, Sivertsson A, Sköllermo A, Steen J, Stenvall M, Sterky F, Strömberg S, Sundberg M, Tegel H, Tourle S, Wahlund E, Waldén A, Wan J, Wernérus H, Westberg J, Wester K, Wrethagen U, Xu LL, Hober S, Pontén F.
A human protein atlas for normal and cancer tissues based on antibody proteomics.
Mol Cell Proteomics. 2005 4(12):1920-32.
PubMed: 16127175 DOI: 10.1074/mcp.M500279-MCP200
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| 6 |
Lindskog M, Rockberg J, Uhlen M, Sterky F.
Selection of protein epitopes for antibody production
Biotechniques 2005 38(5):723-7.
PubMed: 15945371
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| 5 |
Uhlen M, Ponten F.
Antibody-based proteomics for human tissue profiling.
Mol Cell Proteomics. 2005 4(4):384-93.
PubMed: 15695805 DOI: 10.1074/mcp.R500009-MCP200
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| 4 |
Kampf C, Andersson A-C, Wester K, Björling E, Uhlen M, Ponten F
Antibody-based tissue profiling as a tool in clinical proteomics
Clin. Proteomics 2004 1(3-4):285-300.
DOI: 10.1385/CP:1:3-4:285
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| 3 |
Agaton C, Uhlén M, Hober S.
Genome-based proteomics.
Electrophoresis. 2004 25(9):1280-8.
PubMed: 15174050 DOI: 10.1002/elps.200405846
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| 2 |
Agaton C, Falk R, Hoiden Guthenberg I, Gostring L, Uhlen M, Hober S.
Selective enrichment of monospecific polyclonal antibodies for antibody-based proteomics efforts.
J Chromatogr A 2004 16;1043(1):33-40.
PubMed: 15317410
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| 1 |
Agaton C, Galli J, Höidén Guthenberg I, Janzon L, Hansson M, Asplund A, Brundell E, Lindberg S, Ruthberg I, Wester K, Wurtz D, Höög C, Lundeberg J, Ståhl S, Pontén F, Uhlén M.
Affinity proteomics for systematic protein profiling of chromosome 21 gene products in human tissues.
Mol Cell Proteomics. 2003 2(6):405-14.
PubMed: 12796447 DOI: 10.1074/mcp.M300022-MCP200
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