APOC4-APOC2

GENERAL INFORMATION

? »

Gene name

APOC4-APOC2

Gene description

APOC4-APOC2 readthrough (NMD candidate)

Protein class

Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enriched (liver)

Protein evidence

Evidence at protein level

Protein localization

Strong positivity in plasma. Also cytoplasmic expression in liver.

ANTIBODY RELIABILITY

? »

Data reliability
description

Caution, targets protein from more than one gene. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Data reliability

Supportive based on 1 antibody.
HPA055877
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Appendix

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enriched (liver)

Organ

Expression



GENE INFORMATION

? »

Gene name

APOC4-APOC2

Synonyms

Description

APOC4-APOC2 readthrough (NMD candidate) (HGNC Symbol)

Entrez gene summary

This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011]

Chromosome

19

Cytoband

q13.32

Chromosome location (bp)

44942238 - 44949565

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000224916 (version 78.38)

Entrez gene

346

UniProt

neXtProt

Antibodypedia

APOC4-APOC2 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000252490
 
ENST00000589057
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APOC4-APOC2-001 ENSP00000468139
ENST00000589057
K7ER74
Show all »
Show » Show » 178 20 Yes 1
APOC4-APOC2-201 ENSP00000252490
ENST00000252490
A0A024R0T9
Show all »
Show » Show » 101 11.3 Yes 0