CERS1

GENE INFORMATION

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Gene name

CERS1 (HGNC Symbol)

Synonyms

LAG1, LASS1, UOG1

Description

Ceramide synthase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.11

Chromosome location (bp)

18868545 - 18896727

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000223802 (version 78.38)

Entrez gene

10715

UniProt

P27544 (UniProt - Evidence at protein level)

neXtProt

NX_P27544

Antibodypedia

CERS1 antibodies
 

PROTEIN VIEW

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CERS1-001
 
CERS1-002
 
CERS1-004
 
CERS1-005
 
CERS1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CERS1-001 ENSP00000437648
ENST00000542296
Q5XG75
Show all »
Show » Show » 239 27.9 No 6
CERS1-002 ENSP00000389044
ENST00000429504
P27544
Show all »
Show » Show » 337 38 No 6
CERS1-004 ENSP00000471428
ENST00000596048
Show » Show » 216 24.7 No 5
CERS1-005 ENSP00000485308
ENST00000623882
Q5XG75
Show all »
Show » Show » 350 39.5 No 7
CERS1-201 ENSP00000485582
ENST00000623927
A0A024R7N8
Show all »
Show » Show » 372 39.5 Yes 0