PRSS1

GENE INFORMATION

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Gene name

PRSS1 (HGNC Symbol)

Synonyms

TRY1

Description

Protease, serine, 1 (trypsin 1) (HGNC Symbol)

Entrez gene summary

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q34

Chromosome location (bp)

142749468 - 142763997

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204983 (version 78.38)

Entrez gene

5644

UniProt

P07477 (UniProt - Evidence at protein level)

neXtProt

NX_P07477

Antibodypedia

PRSS1 antibodies
 

PROTEIN VIEW

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PRSS1-001
 
PRSS1-003
 
PRSS1-004
 
PRSS1-201
 
PRSS1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRSS1-001 ENSP00000308720
ENST00000311737
P07477
Show all »
Show » Show » 247 26.6 Yes 0
PRSS1-003 ENSP00000417854
ENST00000486171
E7EQ64
Show all »
Show » Show » 261 28.1 Yes 0
PRSS1-004 ENSP00000419912
ENST00000492062
H0Y8D1
Show all »
Show » Show » 142 15.4 No 0
PRSS1-201 ENSP00000479959
ENST00000612126
H0Y8D1
Show all »
Show » Show » 247 26.6 Yes 0
PRSS1-202 ENSP00000481361
ENST00000619214
A6XGL3
Show all »
Show » Show » 237 25.4 Yes 0