AIF1

GENERAL INFORMATION

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Gene name

AIF1

Gene description

Allograft inflammatory factor 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Distinct expression in immune cells in several tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Supportive based on 1 antibody.
HPA049234
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

AIF1 (HGNC Symbol)

Synonyms

AIF-1, Em:AF129756.17, IBA1, IRT-1

Description

Allograft inflammatory factor 1 (HGNC Symbol)

Entrez gene summary

This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Chromosome

6

Cytoband

p21.33

Chromosome location (bp)

31615184 - 31617021

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204472 (version 78.38)

Entrez gene

199

UniProt

P55008 (UniProt - Evidence at protein level)

neXtProt

NX_P55008

Antibodypedia

AIF1 antibodies


PROTEIN BROWSER

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ENST00000337917
 
ENST00000376049
 
ENST00000376059
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AIF1-001 ENSP00000365227
ENST00000376059
P55008
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Show » Show » 147 16.7 No 0
AIF1-002 ENSP00000365217
ENST00000376049
I3WTX1
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Show » Show » 93 10.5 No 0
AIF1-004 ENSP00000338776
ENST00000337917
Q5STX8
Show all »
Show » Show » 161 18 No 0