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protein_class:NEK Ser/Thr protein kinases AND with_antibodies:Yes AND ih_tissue_reliability:Supportive AND is_premium:yes
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Gene name
Protein class
Chromosome
External id
—
Premium atlas
Has protein data
—
IH Tissue reliability
IH Cell reliability
Mouse Brain reliability
IF reliability
IF GFP validation
IF siRNA validation
WB siRNA validation
WB validation
PA validation
—
Subcellular location (IF)
Cell expression (IH)
Tissue expression (IH)
Tissue specificity (RNA)
Tissue detectable (RNA)
—
Evidence summary
UniProt evidence
HPA evidence
MS evidence
—
With antibodies
With annotated expression (IH)
With annotated expression (IF)
—
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Term
Gene name
Class
Enzymes
CD markers
Blood group antigen proteins
Nuclear receptors
Transporters
Ribosomal proteins
G-protein coupled receptors
Voltage-gated ion channels
Predicted membrane proteins
Predicted secreted proteins
Predicted intracellular proteins
Plasma proteins
Transcription factors
Mitochondrial proteins
RNA polymerase related proteins
RAS pathway related proteins
Citric acid cycle related proteins
Cytoskeleton related proteins
Cancer-related genes
Candidate cardiovascular disease genes
Disease related genes
FDA approved drug targets
Potential drug targets
Mapped to UniProt SWISS-PROT
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Subclass
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
MT
Unmapped
X
Y
External id
Is premium
Yes
No
In atlas
Tissue
Cancer
Cell
Subcell
Reliability
Supportive
Uncertain
Validation
Supportive
Uncertain
Reliability
Supportive
Uncertain
Reliability
Supportive
Uncertain
Validation
Supportive
Uncertain
Validation
Supportive
Uncertain
Validation
Supportive
Uncertain
Validation
Supportive
Uncertain
Non-supportive
Validation
Supportive
Uncertain
Location
Nucleus
Nucleoli
Nucleus but not nucleoli
Nuclear membrane
Plasma membrane
Cytoplasm
Mitochondria
Endoplasmic reticulum
Golgi apparatus
Vesicles
Microtubule organizing center
Cytoskeleton (Actin filaments)
Cytoskeleton (Intermediate filaments)
Cytoskeleton (Microtubules)
Cytoskeleton (Cytokinetic bridge)
Cytoskeleton (Microtubule end)
Centrosome
Focal Adhesions
Cell Junctions
Aggresome
Cell
Any
A-431
A549
AN3-CA
BEWO
CACO-2
CAPAN-2
Daudi
EFO-21
HaCaT
HDLM-2
HEK 293
HEL
HeLa
Hep G2
HL-60
HMC-1
HTh 83
K-562
Karpas-707
Leukemia, AML
Leukemia, B-ALL
Leukemia, B-CLL
Leukemia, CML
Leukemia, T-ALL
LP-1
MCF7
MOLT-4
NB-4
NTERA-2
PBMC
PC-3
REH
RH-30
RPMI-8226
RT4
SCLC-21H
SH-SY5Y
SiHa
SK-BR-3
SK-MEL-30
THP-1
TIME
U-138 MG
U-2 OS
U-2197
U-251 MG
U-266/70
U-266/84
U-698
U-87 MG
U-937
WM-115
Expression
Not detected
Low
Medium
High
Tissue
Any
Adrenal gland
Appendix
Bone marrow
Breast
Bronchus
Cerebellum
Cerebral cortex
Cervix, uterine
Colon
Duodenum
Endometrium 1
Endometrium 2
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart muscle
Hippocampus
Kidney
Lateral ventricle
Liver
Lung
Lymph node
Nasopharynx
Oral mucosa
Ovary
Pancreas
Parathyroid gland
Placenta
Prostate
Rectum
Salivary gland
Seminal vesicle
Skeletal muscle
Skin 1
Skin 2
Small intestine
Smooth muscle
Soft tissue 1
Soft tissue 2
Spleen
Stomach 1
Stomach 2
Testis
Thyroid gland
Tonsil
Urinary bladder
Vagina
Cell type
Expression
Not detected
Low
Medium
High
Tissue
Any
Adipose tissue
Adrenal gland
Appendix
Bone marrow
Cerebral cortex
Colon
Duodenum
Endometrium
Esophagus
Fallopian tube
Gallbladder
Heart muscle
Kidney
Liver
Lung
Lymph node
Ovary
Pancreas
Placenta
Prostate
Rectum
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Spleen
Stomach
Testis
Thyroid gland
Tonsil
Urinary bladder
Specificity
Tissue enriched
Group enriched
Tissue enhanced
Elevated
Expressed in all
Mixed
Not detected
Tissue
Any
Adipose tissue
Adrenal gland
Appendix
Bone marrow
Cerebral cortex
Colon
Duodenum
Endometrium
Esophagus
Fallopian tube
Gallbladder
Heart muscle
Kidney
Liver
Lung
Lymph node
Ovary
Pancreas
Placenta
Prostate
Rectum
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Spleen
Stomach
Testis
Thyroid gland
Tonsil
Urinary bladder
Detectable
Yes
No
Category
Evidence at protein level
Evidence at transcript level
No evidence
Score
Evidence at protein level
Evidence at transcript level
No evidence
Score
Evidence at protein level
Evidence at transcript level
No evidence
Score
Evidence at protein level
Evidence at transcript level
No evidence
Antibodies
Yes
No
Annotated expression
Yes
No
Annotated expression
Yes
No
Column
gene
position
tissue specific score
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