AKR1C3

CANCER ATLAS

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Gene description

Aldo-keto reductase family 1, member C3

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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CAB010874
 

Tissue

Cancer staining

Normal tissue
staining

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Normal tissue
staining

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Malignancies showed distinct nuclear and cytoplasmic staining in fractions of cases while the remaining cases were negative. Distinct immunoreactivity was for example observed in most malignant gliomas, liver and urothelial cancers. Malignant melanomas, skin and testicular cancers were negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected