CHRM2

GENE INFORMATION

? »

Gene name

CHRM2

Synonyms

Description

Cholinergic receptor, muscarinic 2 (HGNC Symbol)

Entrez gene summary

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q33

Chromosome location (bp)

136868669 - 137020255

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000181072 (version 78.38)

Entrez gene

1129

UniProt

P08172 (UniProt - Evidence at protein level)

neXtProt

NX_P08172

Antibodypedia

CHRM2 antibodies
 

PROTEIN VIEW

? »
 
 
 
CHRM2-001
 
CHRM2-003
 
CHRM2-004
 
CHRM2-007
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHRM2-001 ENSP00000399745
ENST00000445907
P08172
Show all »
Show » Show » 466 51.7 No 7
CHRM2-003 ENSP00000384401
ENST00000401861
P08172
Show all »
Show » Show » 466 51.7 No 7
CHRM2-004 ENSP00000415386
ENST00000453373
P08172
Show all »
Show » Show » 466 51.7 No 7
CHRM2-007 ENSP00000319984
ENST00000320658
P08172
Show all »
Show » Show » 466 51.7 No 7