JUN

GENERAL INFORMATION

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Gene name

JUN

Gene description

Jun proto-oncogene

Protein class

Cancer-related genes
FDA approved drug targets
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression in several tissues, often only in a fraction of the cells. High expression in squamous epithelia, no expression in lymphoid tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
CAB003801 , CAB007780
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

JUN (HGNC Symbol)

Synonyms

AP-1, c-Jun

Description

Jun proto-oncogene (HGNC Symbol)

Entrez gene summary

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p32.1

Chromosome location (bp)

58780788 - 58784327

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000177606 (version 78.38)

Entrez gene

3725

UniProt

P05412 (UniProt - Evidence at protein level)

neXtProt

NX_P05412

Antibodypedia

JUN antibodies


PROTEIN BROWSER

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ENST00000371222
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

JUN-001 ENSP00000360266
ENST00000371222
P05412
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