CLP1

GENE INFORMATION

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Gene name

CLP1 (HGNC Symbol)

Synonyms

hClp1, HEAB

Description

Cleavage and polyadenylation factor I subunit 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

Chromosome

11

Cytoband

q12.1

Chromosome location (bp)

57648992 - 57661868

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172409 (version 78.38)

Entrez gene

10978

UniProt

Q92989 (UniProt - Evidence at protein level)

neXtProt

NX_Q92989

Antibodypedia

CLP1 antibodies
 

PROTEIN VIEW

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CLP1-001
 
CLP1-002
 
CLP1-003
 
CLP1-004
 
CLP1-005
 
CLP1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLP1-001 ENSP00000434995
ENST00000533682
Q92989
Show all »
Show » Show » 425 47.6 No 0
CLP1-002 ENSP00000436066
ENST00000525602
Q92989
Show all »
Show » Show » 425 47.6 No 0
CLP1-003 ENSP00000304704
ENST00000302731
Q92989
Show all »
Show » Show » 361 40.7 No 0
CLP1-004 ENSP00000433406
ENST00000529430
E9PL17
Show all »
Show » Show » 436 48.9 No 0
CLP1-005 ENSP00000431744
ENST00000533905
E9PJM4
Show all »
Show » 132 14.9 No 0
CLP1-006 ENSP00000435287
ENST00000529773
E9PKV5
Show all »
Show » 92 10.3 No 0