CEBPB

GENERAL INFORMATION

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Gene name

CEBPB

Gene description

CCAAT/enhancer binding protein (C/EBP), beta

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
CAB004213
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Spleen

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

CEBPB (HGNC Symbol)

Synonyms

C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5

Description

CCAAT/enhancer binding protein (C/EBP), beta (HGNC Symbol)

Entrez gene summary

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013]

Chromosome

20

Cytoband

q13.13

Chromosome location (bp)

50190734 - 50192689

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172216 (version 78.38)

Entrez gene

1051

UniProt

P17676 (UniProt - Evidence at protein level)

neXtProt

NX_P17676

Antibodypedia

CEBPB antibodies


PROTEIN BROWSER

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ENST00000303004
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CEBPB-001 ENSP00000305422
ENST00000303004
P17676
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