SEMA3E

GENE INFORMATION

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Gene name

SEMA3E (HGNC Symbol)

Synonyms

coll-5, KIAA0331, M-SemaK, SEMAH

Description

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (HGNC Symbol)

Entrez gene summary

Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]

Chromosome

7

Cytoband

q21.11

Chromosome location (bp)

83363906 - 83649010

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000170381 (version 78.38)

Entrez gene

9723

UniProt

O15041 (UniProt - Evidence at protein level)

neXtProt

NX_O15041

Antibodypedia

SEMA3E antibodies
 

PROTEIN VIEW

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SEMA3E-001
 
SEMA3E-002
 
SEMA3E-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SEMA3E-001 ENSP00000303212
ENST00000307792
O15041
Show all »
Show » Show » 775 89.2 Yes 0
SEMA3E-002 ENSP00000405052
ENST00000427262
O15041
Show all »
Show » Show » 715 82.4 No 0
SEMA3E-004 ENSP00000412867
ENST00000442159
C9JVH5
Show all »
Show » Show » 163 18.7 No 0