SLC30A8

GENE INFORMATION

? »

Gene name

SLC30A8

Synonyms

Description

Solute carrier family 30 (zinc transporter), member 8 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

Chromosome

8

Cytoband

q24.11

Chromosome location (bp)

116950273 - 117176714

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000164756 (version 78.38)

Entrez gene

169026

UniProt

Q8IWU4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8IWU4

Antibodypedia

SLC30A8 antibodies
 

PROTEIN VIEW

? »
 
 
 
SLC30A8-001
 
SLC30A8-002
 
SLC30A8-003
 
SLC30A8-005
 
SLC30A8-006
 
SLC30A8-007
 
SLC30A8-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC30A8-001 ENSP00000431069
ENST00000519688
Q8IWU4
Show all »
Show » Show » 320 35.1 No 6
SLC30A8-002 ENSP00000415011
ENST00000456015
Q8IWU4
Show all »
Show » Show » 369 40.8 No 6
SLC30A8-003 ENSP00000428545
ENST00000521243
Q8IWU4
Show all »
Show » Show » 320 35.1 No 6
SLC30A8-005 ENSP00000427760
ENST00000524274
E5RG87
Show all »
Show » Show » 87 9.5 No 2
SLC30A8-006 ENSP00000485566
ENST00000518521
Show » 52 5.5 No 1
SLC30A8-007 ENSP00000485167
ENST00000518396
Show » 36 4.1 No 0
SLC30A8-201 ENSP00000407505
ENST00000427715
Q8IWU4
Show all »
Show » Show » 320 35.1 No 6