ADCY1

GENERAL INFORMATION

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Gene name

ADCY1

Gene description

Adenylate cyclase 1 (brain)

Protein class

Cancer-related genes
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (cerebral cortex)
GTEx:Group enriched (cerebellum, cerebral cortex, hippocampus, liver)

Protein evidence

Evidence at protein level

Protein localization

RNA-based expert annotation could not be performed.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
CAB018364
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebellum, cerebral cortex, hippocampus, liver)

Organ

Expression



GENE INFORMATION

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Gene name

ADCY1 (HGNC Symbol)

Synonyms

AC1

Description

Adenylate cyclase 1 (brain) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Chromosome

7

Cytoband

p12.3

Chromosome location (bp)

45574140 - 45723116

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164742 (version 78.38)

Entrez gene

107

UniProt

Q08828 (UniProt - Evidence at protein level)

neXtProt

NX_Q08828

Antibodypedia

ADCY1 antibodies


PROTEIN BROWSER

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ENST00000297323
 
ENST00000432715
 
ENST00000621543
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADCY1-001 ENSP00000297323
ENST00000297323
Q08828
Show all »
Show » Show » 1119 123.4 No >9
ADCY1-002 ENSP00000392721
ENST00000432715
C9J1J0
Show all »
Show » Show » 338 38.7 No 0
ADCY1-201 ENSP00000479770
ENST00000621543
C9J1J0
Show all »
Show » Show » 338 38.7 No 0