NKX6-1

GENE INFORMATION

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Gene name

NKX6-1 (HGNC Symbol)

Synonyms

Nkx6.1, NKX6A

Description

NK6 homeobox 1 (HGNC Symbol)

Entrez gene summary

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008]

Chromosome

4

Cytoband

q21.23

Chromosome location (bp)

84491987 - 84498450

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163623 (version 78.38)

Entrez gene

4825

UniProt

P78426 (UniProt - Evidence at transcript level)

neXtProt

NX_P78426

Antibodypedia

NKX6-1 antibodies
 

PROTEIN VIEW

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NKX6-1-001
 
NKX6-1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NKX6-1-001 ENSP00000295886
ENST00000295886
P78426
Show all »
Show » Show » 367 37.8 No 0
NKX6-1-002 ENSP00000449761
ENST00000515820
F8VWZ9
Show all »
Show » Show » 93 10.5 No 0