ADAR

GENERAL INFORMATION

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Gene name

ADAR

Gene description

Adenosine deaminase, RNA-specific

Protein class

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA003890 , HPA051519 , CAB056157
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ADAR (HGNC Symbol)

Synonyms

ADAR1, G1P1, IFI4

Description

Adenosine deaminase, RNA-specific (HGNC Symbol)

Entrez gene summary

This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

154582062 - 154627999

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160710 (version 78.38)

Entrez gene

103

UniProt

P55265 (UniProt - Evidence at protein level)

neXtProt

NX_P55265

Antibodypedia

ADAR antibodies


PROTEIN BROWSER

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ENST00000368471
 
ENST00000368474
 
ENST00000529168
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAR-001 ENSP00000357459
ENST00000368474
P55265
Show all »
Show » Show » 1226 136.1 No 0
ADAR-002 ENSP00000357456
ENST00000368471
P55265
Show all »
Show » Show » 931 103.6 No 0
ADAR-007 ENSP00000431794
ENST00000529168
H0YCK3
Show all »
Show » Show » 1195 132.6 No 0