CNNM4

CANCER ATLAS

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Gene description

Cyclin and CBS domain divalent metal cation transport mediator 4

Protein class

Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Glioma

STAINING SUMMARY

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HPA017732
 

Tissue

Cancer staining

Normal tissue
staining

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Normal tissue
staining

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Malignant gliomas showed strong cytoplasmic staining. Moderate cytoplasmic and membranous positivity was observed in colorectal, breast and ovarian cancers as well as several cervical, lung, testicular, gastric and pancreatic cancers. Remaining malignancies were in general weakly stained or negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected