FGF18

GENE INFORMATION

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Gene name

FGF18 (HGNC Symbol)

Synonyms

FGF-18, ZFGF5

Description

Fibroblast growth factor 18 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q35.1

Chromosome location (bp)

171419656 - 171457623

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000156427 (version 78.38)

Entrez gene

8817

UniProt

O76093 (UniProt - Evidence at protein level)

neXtProt

NX_O76093

Antibodypedia

FGF18 antibodies
 

PROTEIN VIEW

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FGF18-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF18-001 ENSP00000274625
ENST00000274625
O76093
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