SCN3A

CANCER ATLAS

? »

Gene description

Sodium channel, voltage-gated, type III, alpha subunit

Protein class

FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

? »
 
 
HPA035396
 

Tissue

Cancer staining

Normal tissue
staining

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Normal tissue
staining

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Tumour tissues displayed weak to moderate cytoplasmic positivity. Nucleolar staining was observed in a few cases of melanoma and breast cancer. Occasional cases of thyroid, prostate, ovarian and skin cancers were strongly stained. Many cases of lymphomas, renal, liver and cervical cancers were negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected