DCUN1D2

CANCER ATLAS

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Gene description

DCN1, defective in cullin neddylation 1, domain containing 2

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY

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HPA039349
 

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer
 

Staining summary

A single case of duct carcinoma of breast showed strong nuclear staining in a fraction of cells. Thyroid cancers along with a few cases of squamous cell carcinoma, hepatocellular carcinoma, colorectal and ovarian cancers showed moderate cytoplasmic positivity. Extracellular material were distinctly stained in several cases. Remaining malignant cells were weakly stained or negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected