CNNM2

GENE INFORMATION

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Gene name

CNNM2 (HGNC Symbol)

Synonyms

ACDP2

Description

Cyclin and CBS domain divalent metal cation transport mediator 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Chromosome

10

Cytoband

q24.32

Chromosome location (bp)

102918293 - 103090221

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000148842 (version 78.38)

Entrez gene

54805

UniProt

Q9H8M5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H8M5

Antibodypedia

CNNM2 antibodies
 

PROTEIN VIEW

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CNNM2-001
 
CNNM2-002
 
CNNM2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CNNM2-001 ENSP00000358894
ENST00000369878
Q9H8M5
Show all »
Show » Show » 875 96.6 No 5
CNNM2-002 ENSP00000392875
ENST00000433628
Q9H8M5
Show all »
Show » Show » 853 94.3 No 5
CNNM2-004 ENSP00000358891
ENST00000369875
Q9H8M5
Show all »
Show » Show » 552 60.5 No 5