ANKRD1

GENERAL INFORMATION

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Gene name

ANKRD1

Gene description

Ankyrin repeat domain 1 (cardiac muscle)

Protein class

Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (heart muscle)
GTEx:Group enriched (heart muscle)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in heart muscle.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA038736
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (heart muscle)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (heart muscle)

Organ

Expression



GENE INFORMATION

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Gene name

ANKRD1 (HGNC Symbol)

Synonyms

ALRP, C-193, CARP, CVARP, MCARP

Description

Ankyrin repeat domain 1 (cardiac muscle) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

q23.31

Chromosome location (bp)

90912096 - 90921276

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000148677 (version 78.38)

Entrez gene

27063

UniProt

Q15327 (UniProt - Evidence at protein level)

neXtProt

NX_Q15327

Antibodypedia

ANKRD1 antibodies


PROTEIN BROWSER

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ENST00000371697
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANKRD1-001 ENSP00000360762
ENST00000371697
Q15327
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