PSMB6

GENE INFORMATION

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Gene name

PSMB6 (HGNC Symbol)

Synonyms

DELTA, Y

Description

Proteasome (prosome, macropain) subunit, beta type, 6 (HGNC Symbol)

Entrez gene summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Chromosome

17

Cytoband

p13.2

Chromosome location (bp)

4796144 - 4798503

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142507 (version 78.38)

Entrez gene

5694

UniProt

P28072 (UniProt - Evidence at protein level)

neXtProt

NX_P28072

Antibodypedia

PSMB6 antibodies
 

PROTEIN VIEW

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PSMB6-001
 
PSMB6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMB6-001 ENSP00000270586
ENST00000270586
P28072
Show all »
Show » Show » 239 25.4 No 0
PSMB6-201 ENSP00000485006
ENST00000614486
Show » Show » 213 23.1 No 0