ADAMTS10

GENE INFORMATION

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Gene name

ADAMTS10 (HGNC Symbol)

Synonyms

ADAM-TS10

Description

ADAM metallopeptidase with thrombospondin type 1 motif, 10 (HGNC Symbol)

Entrez gene summary

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

8580242 - 8610735

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142303 (version 78.38)

Entrez gene

81794

UniProt

Q9H324 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H324

Antibodypedia

ADAMTS10 antibodies
 

PROTEIN VIEW

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ADAMTS10-001
 
ADAMTS10-003
 
ADAMTS10-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAMTS10-001 ENSP00000471851
ENST00000597188
Show » Show » 1103 120.9 Yes 0
ADAMTS10-003 ENSP00000470501
ENST00000595838
Q9H324
Show all »
Show » Show » 590 62.5 No 0
ADAMTS10-201 ENSP00000270328
ENST00000270328
Show » Show » 1103 120.9 Yes 0