ACTR1A

GENE INFORMATION

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Gene name

ACTR1A (HGNC Symbol)

Synonyms

ARP1

Description

ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) (HGNC Symbol)

Entrez gene summary

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

q24.32

Chromosome location (bp)

102479229 - 102502711

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000138107 (version 78.38)

Entrez gene

10121

UniProt

P61163 (UniProt - Evidence at protein level)

neXtProt

NX_P61163

Antibodypedia

ACTR1A antibodies
 

PROTEIN VIEW

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ACTR1A-001
 
ACTR1A-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACTR1A-001 ENSP00000358921
ENST00000369905
P61163
Show all »
Show » Show » 376 42.6 No 0
ACTR1A-002 ENSP00000473334
ENST00000487599
R4GMT0
Show all »
Show » 332 37.4 No 0