ITPKA

GENE INFORMATION

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Gene name

ITPKA (HGNC Symbol)

Synonyms

IP3-3KA, IP3KA

Description

Inositol-trisphosphate 3-kinase A (HGNC Symbol)

Entrez gene summary

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011]

Chromosome

15

Cytoband

q15.1

Chromosome location (bp)

41493393 - 41503551

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137825 (version 78.38)

Entrez gene

3706

UniProt

P23677 (UniProt - Evidence at protein level)

neXtProt

NX_P23677

Antibodypedia

ITPKA antibodies
 

PROTEIN VIEW

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ITPKA-001
 
ITPKA-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITPKA-001 ENSP00000260386
ENST00000260386
P23677
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Show » Show » 461 51 No 0
ITPKA-002 ENSP00000396560
ENST00000425927
C9JC74
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Show » Show » 260 29.3 No 0