SP110

GENE INFORMATION

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Gene name

SP110 (HGNC Symbol)

Synonyms

IFI41, IFI75

Description

SP110 nuclear body protein (HGNC Symbol)

Entrez gene summary

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q37.1

Chromosome location (bp)

230167293 - 230225729

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135899 (version 78.38)

Entrez gene

3431

UniProt

Q9HB58 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HB58

Antibodypedia

SP110 antibodies
 

PROTEIN VIEW

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SP110-001
 
SP110-002
 
SP110-003
 
SP110-004
 
SP110-006
 
SP110-007
 
SP110-008
 
SP110-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SP110-001 ENSP00000258382
ENST00000258382
Q9HB58
Show all »
Show » Show » 549 61.9 No 0
SP110-002 ENSP00000258381
ENST00000258381
Q9HB58
Show all »
Show » Show » 713 81.2 No 0
SP110-003 ENSP00000351488
ENST00000358662
Q9HB58
Show all »
Show » Show » 689 78.4 No 0
SP110-004 ENSP00000375902
ENST00000392048
G5E9C0
Show all »
Show » Show » 547 61.7 No 0
SP110-006 ENSP00000399978
ENST00000416610
E9PHK4
Show all »
Show » Show » 101 12 No 0
SP110-007 ENSP00000387172
ENST00000409815
E7EM70
Show all »
Show » Show » 221 24.6 No 0
SP110-008 ENSP00000393992
ENST00000455674
C9JZQ4
Show all »
Show » Show » 160 17.6 No 0
SP110-201 ENSP00000439558
ENST00000540870
Q9HB58
Show all »
Show » Show » 555 62.6 No 0