CD36

GENERAL INFORMATION

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Gene name

CD36

Gene description

CD36 molecule (thrombospondin receptor)

Protein class

Cancer-related genes
CD markers
Disease related genes
Plasma proteins
Potential drug targets
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

17
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Group enriched (adipose tissue, breast, heart muscle, spleen)

Protein evidence

Evidence at protein level

Protein localization

Distinct expression in endothelium, adipocytes, trombocytes, megakaryocytes, skeletal and heart muscle.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA002018 , CAB025866
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Soft tissue



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (adipose tissue, breast, heart muscle, spleen)

Organ

Expression



GENE INFORMATION

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Gene name

CD36 (HGNC Symbol)

Synonyms

FAT, GP3B, GP4, GPIV, SCARB3

Description

CD36 molecule (thrombospondin receptor) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

Chromosome

7

Cytoband

q21.11

Chromosome location (bp)

80369575 - 80679277

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135218 (version 78.38)

Entrez gene

948

UniProt

P16671 (UniProt - Evidence at protein level)

neXtProt

NX_P16671

Antibodypedia

CD36 antibodies


PROTEIN BROWSER

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ENST00000309881
 
ENST00000394788
 
ENST00000413265
 
ENST00000419819
 
ENST00000426978
 
ENST00000428497
 
ENST00000432207
 
ENST00000433696
 
ENST00000435819
 
ENST00000436384
 
ENST00000438020
 
ENST00000447544
 
ENST00000482059
 
ENST00000488048
 
ENST00000534394
 
ENST00000538969
 
ENST00000544133
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD36-001 ENSP00000399421
ENST00000435819
P16671
Show all »
Show » Show » 472 53.1 No 2
CD36-002 ENSP00000416388
ENST00000426978
E7EWI4
Show all »
Show » Show » 148 16.2 No 1
CD36-003 ENSP00000407690
ENST00000413265
E7EX47
Show all »
Show » Show » 203 22.7 No 1
CD36-004 ENSP00000410371
ENST00000438020
E7ERZ9
Show all »
Show » Show » 143 15.7 No 1
CD36-005 ENSP00000409762
ENST00000428497
E9PC45
Show all »
Show » Show » 93 10.3 No 1
CD36-006 ENSP00000308165
ENST00000309881
P16671
Show all »
Show » Show » 472 53.1 No 2
CD36-007 ENSP00000398760
ENST00000436384
E9PC45
Show all »
Show » Show » 93 10.3 No 1
CD36-009 ENSP00000433659
ENST00000482059
E9PJX8
Show all »
Show » Show » 65 7 No 1
CD36-012 ENSP00000392298
ENST00000419819
E7EU05
Show all »
Show » Show » 463 52.1 No 2
CD36-015 ENSP00000415743
ENST00000447544
P16671
Show all »
Show » Show » 472 53.1 No 2
CD36-016 ENSP00000378268
ENST00000394788
P16671
Show all »
Show » Show » 472 53.1 No 2
CD36-017 ENSP00000435698
ENST00000488048
Show » Show » 66 7.3 No 1
CD36-019 ENSP00000431296
ENST00000534394
E9PLT1
Show all »
Show » Show » 396 44.7 No 1
CD36-201 ENSP00000411411
ENST00000432207
P16671
Show all »
Show » Show » 472 53.1 No 2
CD36-202 ENSP00000401863
ENST00000433696
P16671
Show all »
Show » Show » 433 48.6 No 2
CD36-203 ENSP00000439543
ENST00000538969
P16671
Show all »
Show » Show » 412 46.1 No 2
CD36-204 ENSP00000441956
ENST00000544133
P16671
Show all »
Show » Show » 288 32.3 No 1