CDC73

GENE INFORMATION

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Gene name

CDC73 (HGNC Symbol)

Synonyms

C1orf28, FIHP, HRPT1, HRPT2, parafibromin

Description

Cell division cycle 73 (HGNC Symbol)

Entrez gene summary

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]

Chromosome

1

Cytoband

q31.2

Chromosome location (bp)

193122017 - 193253901

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134371 (version 78.38)

Entrez gene

79577

UniProt

Q6P1J9 (UniProt - Evidence at protein level)

neXtProt

NX_Q6P1J9

Antibodypedia

CDC73 antibodies
 

PROTEIN VIEW

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CDC73-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDC73-001 ENSP00000356405
ENST00000367435
Q6P1J9
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