Below to the right is an overview of RNA and protein expression data generated in the HPA project. Analyzed tissues are divided into 13 color-coded groups according to common functional features. For each group, a list of included tissues is accessed by clicking on group name, group symbol, RNA bar or protein bar. Subsequent selection of a particular tissue in this list links to the image data page.

Images of selected tissues give a visual summary of the protein expression profile below to the left. The gray human body in the middle provides links to a histology dictionary when clicking on any part of the figure.

RNA expression (FPKM)

RNA–seq results generated in HPA are reported as number of Fragments Per Kilobase gene model and Million reads (FPKM). The assay is described more in detail in Assays & Annotation.

Protein expression (score)

Each bar represents the highest expression score found in a particular group of tissues. For proteins where the antibody staining pattern has been analyzed by knowledge-based annotation, protein expression scores are based on a best estimate of the "true" protein expression, described more in detail under Assays & annotation. For genes that are pending this extended review, the protein expression scores correspond to the staining profile of the used antibody. For genes where more than one antibody has been used, a common score is set displaying the estimated "true" protein expression.

HPA dataset

RNA-seq data from 32 tissues are reported as mean FPKM (Fragments Per Kilobase gene model and Million reads), corresponding to mean values of the different individual samples from each tissue type. Color-coding is based on 13 tissue groups, each consisting of tissues with common functional features. To access sample data, click on tissue name or bar. The RNA-seq assay is described in detail in Assays & Annotation.

RNA tissue category HPA

HPA RNA tissue category (category description) is calculated based on mRNA expression levels in 32 different tissues and include: tissue enriched, group enriched, tissue enhanced, expressed in all, not detected and mixed.

GTEx dataset

RNA-seq data from 28 tissues are reported as median RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) consortium. More information can be found in Assays & Annotation.

RNA tissue category GTEx

GTEx RNA tissue category (category description) is calculated based on mRNA expression levels in 28 different tissues and include: tissue enriched, group enriched, tissue enhanced, expressed in all, not detected and mixed.