INPP5K

GENERAL INFORMATION

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Gene name

INPP5K

Gene description

Inositol polyphosphate-5-phosphatase K

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Moderate cytoplasmic positivity was observed in the gastrointestinal tract and megakaryocytes in bone marrow. Subsets of stromal inflammatory cells displayed strong staining. Remaining normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA031044
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

INPP5K (HGNC Symbol)

Synonyms

SKIP

Description

Inositol polyphosphate-5-phosphatase K (HGNC Symbol)

Entrez gene summary

This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

Chromosome

17

Cytoband

p13.3

Chromosome location (bp)

1494571 - 1516888

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000132376 (version 78.38)

Entrez gene

51763

UniProt

Q9BT40 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BT40

Antibodypedia

INPP5K antibodies


PROTEIN BROWSER

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ENST00000320345
 
ENST00000406424
 
ENST00000421807
 
ENST00000449479
 
ENST00000477910
 
ENST00000498390
 
ENST00000571274
 
ENST00000574561
 
ENST00000575172
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

INPP5K-001 ENSP00000413937
ENST00000421807
Q9BT40
Show all »
Show » Show » 448 51.1 No 0
INPP5K-003 ENSP00000385177
ENST00000406424
B7Z4V9
Show all »
Show » Show » 372 42.8 No 0
INPP5K-004 ENSP00000318476
ENST00000320345
B7Z4V9
Show all »
Show » Show » 372 42.8 No 0
INPP5K-005 ENSP00000466929
ENST00000498390
K7ENF7
Show all »
Show » 23 2.7 No 0
INPP5K-006 ENSP00000467376
ENST00000477910
K7EPG6
Show all »
Show » 50 5.7 No 0
INPP5K-007 ENSP00000413259
ENST00000449479
C9JZB0
Show all »
Show » Show » 229 26.7 No 0
INPP5K-018 ENSP00000458413
ENST00000571274
I3L0Y0
Show all »
Show » 85 9.7 No 0
INPP5K-021 ENSP00000459758
ENST00000575172
I3L2L1
Show all »
Show » Show » 158 17.9 No 0
INPP5K-022 ENSP00000461105
ENST00000574561
I3L4A5
Show all »
Show » 154 17.4 No 0