PPP1R1B

CANCER ATLAS

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Gene description

Protein phosphatase 1, regulatory (inhibitor) subunit 1B

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Pancreatic cancer

STAINING SUMMARY

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HPA048630
 
 
HPA061142
 
CAB004026
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Colorectal cancers displayed moderate cytoplasmic, membranous and nuclear positivity. Few cases of duct carcinomas of breast, gliomas, prostate, stomach and endometrial cancers showed moderate cytoplasmic and nuclear staining while several cases of pancreatic cancers exhibited moderate to strong positivity. A single case of adenocarcinoma of head and neck showed strong cytoplasmic staining. Remaining cancer tissues were weakly stained or negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected