GCM2

GENE INFORMATION

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Gene name

GCM2 (HGNC Symbol)

Synonyms

GCMB, hGCMb

Description

Glial cells missing homolog 2 (Drosophila) (HGNC Symbol)

Entrez gene summary

This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p24.2

Chromosome location (bp)

10873223 - 10881941

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124827 (version 78.38)

Entrez gene

9247

UniProt

O75603 (UniProt - Evidence at protein level)

neXtProt

NX_O75603

Antibodypedia

GCM2 antibodies
 

PROTEIN VIEW

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GCM2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GCM2-001 ENSP00000368805
ENST00000379491
O75603
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