CDK2

GENE INFORMATION

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Gene name

CDK2

Synonyms

Description

Cyclin-dependent kinase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Chromosome

12

Cytoband

q13.2

Chromosome location (bp)

55966769 - 55972784

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000123374 (version 78.38)

Entrez gene

1017

UniProt

P24941 (UniProt - Evidence at protein level)

neXtProt

NX_P24941

Antibodypedia

CDK2 antibodies
 

PROTEIN VIEW

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CDK2-001
 
CDK2-002
 
CDK2-003
 
CDK2-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDK2-001 ENSP00000266970
ENST00000266970
P24941
Show all »
Show » Show » 298 33.9 No 0
CDK2-002 ENSP00000243067
ENST00000354056
P24941
Show all »
Show » Show » 264 30 No 0
CDK2-003 ENSP00000393605
ENST00000440311
E7ESI2
Show all »
Show » Show » 238 27.2 No 0
CDK2-007 ENSP00000452514
ENST00000553376
G3V5T9
Show all »
Show » Show » 346 39.2 No 0