EGR1

GENERAL INFORMATION

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Gene name

EGR1

Gene description

Early growth response 1

Protein class

Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
CAB019427
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

EGR1 (HGNC Symbol)

Synonyms

AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225

Description

Early growth response 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]

Chromosome

5

Cytoband

q31.2

Chromosome location (bp)

138465490 - 138469315

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000120738 (version 78.38)

Entrez gene

1958

UniProt

P18146 (UniProt - Evidence at protein level)

neXtProt

NX_P18146

Antibodypedia

EGR1 antibodies


PROTEIN BROWSER

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ENST00000239938
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EGR1-001 ENSP00000239938
ENST00000239938
P18146
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