ACAT2

CANCER ATLAS

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Gene description

Acetyl-CoA acetyltransferase 2

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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HPA025736
 
 
HPA025765
 
HPA025811
 
CAB021106
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Weak to moderate cytoplasmic positivity was observed in a most malignancies. A few cases of malignant gliomas, testicular, urothelial and liver cancers showed strong cytoplasmic positivity combined with a few cases of nuclear staining. Renal cancer and malignant melanomas were generally negative. Most malignancies were weak to moderately stained. Cases of malignant gliomas, testicular, liver and urothelial cancers displayed strong positivity. Malignant melanomas, malignant lymphomas, squamous cell carcinomas, renal and endometrial cancers showed many unstained cases.
 

Level of antibody staining/expression





High
Medium
Low
Not detected