CREB1

GENERAL INFORMATION

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Gene name

CREB1

Gene description

CAMP responsive element binding protein 1

Protein class

Cancer-related genes
Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

10
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA019150 , CAB003803
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

CREB1

Synonyms

Description

CAMP responsive element binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q33.3

Chromosome location (bp)

207529737 - 207603431

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000118260 (version 78.38)

Entrez gene

1385

UniProt

P16220 (UniProt - Evidence at protein level)

neXtProt

NX_P16220

Antibodypedia

CREB1 antibodies


PROTEIN BROWSER

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ENST00000353267
 
ENST00000414681
 
ENST00000421139
 
ENST00000430624
 
ENST00000432329
 
ENST00000445803
 
ENST00000448277
 
ENST00000452474
 
ENST00000455757
 
ENST00000457101
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CREB1-001 ENSP00000387699
ENST00000432329
P16220
Show all »
Show » Show » 341 36.7 No 0
CREB1-002 ENSP00000236995
ENST00000353267
P16220
Show all »
Show » Show » 327 35.1 No 0
CREB1-003 ENSP00000405539
ENST00000430624
P16220
Show all »
Show » Show » 327 35.1 No 0
CREB1-005 ENSP00000407227
ENST00000445803
E7EWP8
Show all »
Show » Show » 182 19.5 No 0
CREB1-006 ENSP00000392428
ENST00000452474
C9J276
Show all »
Show » Show » 132 14 No 0
CREB1-007 ENSP00000403678
ENST00000421139
C9JBT4
Show all »
Show » Show » 170 18 No 0
CREB1-009 ENSP00000404890
ENST00000414681
C9JCI4
Show all »
Show » 79 8.1 No 0
CREB1-010 ENSP00000391125
ENST00000457101
C9J4L5
Show all »
Show » Show » 131 14.1 No 0
CREB1-011 ENSP00000405711
ENST00000448277
C9J896
Show all »
Show » Show » 251 26.7 No 0
CREB1-016 ENSP00000401803
ENST00000455757
H7C1R5
Show all »
Show » Show » 140 14.7 No 0