MEF2D

GENE INFORMATION

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Gene name

MEF2D

Synonyms

Description

Myocyte enhancer factor 2D (HGNC Symbol)

Entrez gene summary

This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]

Chromosome

1

Cytoband

q22

Chromosome location (bp)

156463727 - 156500828

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116604 (version 78.38)

Entrez gene

4209

UniProt

Q14814 (UniProt - Evidence at protein level)

neXtProt

NX_Q14814

Antibodypedia

MEF2D antibodies
 

PROTEIN VIEW

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MEF2D-001
 
MEF2D-004
 
MEF2D-005
 
MEF2D-006
 
MEF2D-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MEF2D-001 ENSP00000271555
ENST00000348159
Q14814
Show all »
Show » Show » 521 55.9 No 0
MEF2D-004 ENSP00000353803
ENST00000360595
Q14814
Show all »
Show » Show » 514 55.1 No 0
MEF2D-005 ENSP00000476788
ENST00000464356
Q14814
Show all »
Show » Show » 513 55.3 No 0
MEF2D-006 ENSP00000477124
ENST00000489057
Show » 10 1.3 No 0
MEF2D-201 ENSP00000357223
ENST00000368240
Q05BX2
Show all »
Show » Show » 139 16.2 No 0