CCND3

GENE INFORMATION

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Gene name

CCND3

Synonyms

Description

Cyclin D3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Chromosome

6

Cytoband

p21.1

Chromosome location (bp)

41934933 - 42050357

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112576 (version 78.38)

Entrez gene

896

UniProt

P30281 (UniProt - Evidence at protein level)

neXtProt

NX_P30281

Antibodypedia

CCND3 antibodies
 

PROTEIN VIEW

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 « 
 
CCND3-001
 
CCND3-002
 
CCND3-003
 
CCND3-005
 
CCND3-006
 
CCND3-007
 
CCND3-011
 
CCND3-012
 
CCND3-013
 
CCND3-014
 
CCND3-019
 
CCND3-020
 
CCND3-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCND3-001 ENSP00000362082
ENST00000372991
P30281
Show all »
Show » Show » 292 32.5 No 0
CCND3-002 ENSP00000362078
ENST00000372987
Q5T8J1
Show all »
Show » Show » 242 26.2 No 0
CCND3-003 ENSP00000397545
ENST00000414200
P30281
Show all »
Show » Show » 220 24.2 No 0
CCND3-005 ENSP00000426212
ENST00000511642
P30281
Show all »
Show » Show » 211 22.9 No 0
CCND3-006 ENSP00000362079
ENST00000372988
P30281
Show all »
Show » Show » 211 22.9 No 0
CCND3-007 ENSP00000401595
ENST00000415497
P30281
Show all »
Show » Show » 96 9.7 No 0
CCND3-011 ENSP00000423242
ENST00000508143
Show » 10 1.1 No 0
CCND3-012 ENSP00000425334
ENST00000502771
D6RDL3
Show all »
Show » Show » 43 4.9 No 0
CCND3-013 ENSP00000420991
ENST00000514588
D6RDF8
Show all »
Show » Show » 47 5.3 No 0
CCND3-014 ENSP00000425830
ENST00000505064
D6RIX2
Show all »
Show » Show » 118 13.6 No 0
CCND3-019 ENSP00000421511
ENST00000512426
H0Y8M4
Show all »
Show » Show » 175 19.2 No 0
CCND3-020 ENSP00000425986
ENST00000510503
D6RI00
Show all »
Show » Show » 195 21.7 No 0
CCND3-201 ENSP00000484424
ENST00000616010
P30281
Show all »
Show » Show » 96 9.7 No 0