ARHGDIB

GENE INFORMATION

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Gene name

ARHGDIB (HGNC Symbol)

Synonyms

GDIA2, GDID4, Ly-GDI, RAP1GN1, RhoGDI2

Description

Rho GDP dissociation inhibitor (GDI) beta (HGNC Symbol)

Entrez gene summary

Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]

Chromosome

12

Cytoband

p12.3

Chromosome location (bp)

14942017 - 14961728

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111348 (version 78.38)

Entrez gene

397

UniProt

P52566 (UniProt - Evidence at protein level)

neXtProt

NX_P52566

Antibodypedia

ARHGDIB antibodies
 

PROTEIN VIEW

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ARHGDIB-001
 
ARHGDIB-002
 
ARHGDIB-003
 
ARHGDIB-004
 
ARHGDIB-005
 
ARHGDIB-006
 
ARHGDIB-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGDIB-001 ENSP00000228945
ENST00000228945
P52566
Show all »
Show » Show » 201 23 No 0
ARHGDIB-002 ENSP00000440560
ENST00000541546
P52566
Show all »
Show » Show » 201 23 No 0
ARHGDIB-003 ENSP00000445450
ENST00000542276
F5H2R5
Show all »
Show » Show » 88 9.8 No 0
ARHGDIB-004 ENSP00000437454
ENST00000541380
F5H6Q0
Show all »
Show » Show » 112 12.5 No 0
ARHGDIB-005 ENSP00000445263
ENST00000545895
F5H3P3
Show all »
Show » Show » 159 17.9 No 0
ARHGDIB-006 ENSP00000444860
ENST00000541644
P52566
Show all »
Show » Show » 201 23 No 0
ARHGDIB-008 ENSP00000445185
ENST00000536592
Show » Show » 195 22.3 No 0