PORCN

GENE INFORMATION

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Gene name

PORCN (HGNC Symbol)

Synonyms

DHOF, MG61, por, PORC, PPN

Description

Porcupine homolog (Drosophila) (HGNC Symbol)

Entrez gene summary

This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2013]

Chromosome

X

Cytoband

p11.23

Chromosome location (bp)

48508962 - 48520814

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102312 (version 78.38)

Entrez gene

64840

UniProt

Q9H237 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H237

Antibodypedia

PORCN antibodies
 

PROTEIN VIEW

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PORCN-001
 
PORCN-002
 
PORCN-008
 
PORCN-010
 
PORCN-011
 
PORCN-201
 
PORCN-202
 
PORCN-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PORCN-001 ENSP00000352946
ENST00000359882
Q9H237
Show all »
Show » Show » 455 51.6 No 8
PORCN-002 ENSP00000348233
ENST00000355961
Q9H237
Show all »
Show » Show » 456 51.8 No 8
PORCN-008 ENSP00000419212
ENST00000489940
C9JWI5
Show all »
Show » 97 11.2 No 2
PORCN-010 ENSP00000354978
ENST00000361988
Q9H237
Show all »
Show » Show » 450 51 No 8
PORCN-011 ENSP00000322304
ENST00000326194
Q9H237
Show all »
Show » Show » 461 52.3 No 8
PORCN-201 ENSP00000347207
ENST00000355092
Show » 405 45.8 No 8
PORCN-202 ENSP00000356546
ENST00000367574
Q9H237
Show all »
Show » Show » 455 51.6 No 9
PORCN-203 ENSP00000446401
ENST00000537758
Q9H237
Show all »
Show » Show » 456 51.8 No 9