EFNA2

GENE INFORMATION

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Gene name

EFNA2 (HGNC Symbol)

Synonyms

ELF-1, EPLG6, LERK6

Description

Ephrin-A2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

1286154 - 1300237

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000099617 (version 78.38)

Entrez gene

1943

UniProt

O43921 (UniProt - Evidence at protein level)

neXtProt

NX_O43921

Antibodypedia

EFNA2 antibodies
 

PROTEIN VIEW

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EFNA2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EFNA2-001 ENSP00000215368
ENST00000215368
O43921
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