CD82

GENE INFORMATION

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Gene name

CD82 (HGNC Symbol)

Synonyms

IA4, KAI1, R2, ST6, TSPAN27

Description

CD82 molecule (HGNC Symbol)

Entrez gene summary

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p11.2

Chromosome location (bp)

44564427 - 44620363

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000085117 (version 78.38)

Entrez gene

3732

UniProt

P27701 (UniProt - Evidence at protein level)

neXtProt

NX_P27701

Antibodypedia

CD82 antibodies
 

PROTEIN VIEW

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CD82-001
 
CD82-002
 
CD82-003
 
CD82-004
 
CD82-005
 
CD82-008
 
CD82-009
 
CD82-011
 
CD82-012
 
CD82-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD82-001 ENSP00000227155
ENST00000227155
P27701
Show all »
Show » Show » 267 29.6 No 4
CD82-002 ENSP00000339686
ENST00000342935
P27701
Show all »
Show » Show » 242 26.8 No 3
CD82-003 ENSP00000435661
ENST00000525210
E9PJ59
Show all »
Show » Show » 38 4.3 No 1
CD82-004 ENSP00000431767
ENST00000532544
E9PJK9
Show all »
Show » Show » 108 11.7 No 3
CD82-005 ENSP00000433151
ENST00000527737
E9PM43
Show all »
Show » Show » 179 19.4 Yes 3
CD82-008 ENSP00000435682
ENST00000526958
E9PJ45
Show all »
Show » Show » 161 17.2 No 3
CD82-009 ENSP00000433804
ENST00000525813
E9PJB7
Show all »
Show » Show » 105 11.2 No 3
CD82-011 ENSP00000433036
ENST00000524750
H0YD57
Show all »
Show » 57 6.5 No 0
CD82-012 ENSP00000433788
ENST00000530601
E9PJC7
Show all »
Show » Show » 157 17.3 No 3
CD82-013 ENSP00000436403
ENST00000524704
E9PP61
Show all »
Show » Show » 68 7.4 No 2